褐藻多酚的毒理学研究  

TOXICOLOGICAL STUDY ON BROWN ALGAL POLYPHENOLS

作　　者：娄清香[1] 严小军[1] 

机构地区：[1]中国科学院海洋洋研究所,青岛266071

出　　处：《海洋科学》2000年第9期53-55,共3页Marine Sciences

基　　金：国家九五攻关项目!966 916 04 01号;中国科学院海洋研究所调查研究报告第3834号

摘　　要：To determine the diet security of brown algal polyphenols, we studied the acute toxicity and 90 day’s feed toxicity on brown algal polyphenols isolated from Sargassum kjellmanianum. The lethal dose 50 for rat is 1 230×10-6,with 95% confidence ranged from 791.4×10-6 to 1 912.4×10-6. The 90 day′s feeding experiment showed that the mouses administered brown algal polyphenols maintain regular conditions, with no difference to the control group on blood biochemical index, weight, and pathology analysis. The results indicated that brown algal polyphenols is safe as food additive.To determine the diet security of brown algal polyphenols, we studied the acute toxicity and 90 day's feed toxicity on brown algal polyphenols isolated from Sargassum kjellmanianum. The lethal dose 50 for rat is 1 230×10-6,with 95% confidence ranged from 791.4×10-6 to 1 912.4×10-6. The 90 day′s feeding experiment showed that the mouses administered brown algal polyphenols maintain regular conditions, with no difference to the control group on blood biochemical index, weight, and pathology analysis. The results indicated that brown algal polyphenols is safe as food additive.

关 键 词：褐藻多酚 食用安全性 毒理 

分 类 号：R996.2[医药卫生—毒理学]