彩色多普勒超声诊断甲状腺结节的价值  

Value of color Doppler ultrasound in diagnosis of thyroid nodules

作　　者：胡杨志[1] 潘运龙[1] 赵晓旭[1] 覃莉[2] 巫青[1] 丁晖[1] 

机构地区：[1]暨南大学附属第一医院普外科,广东广州510632 [2]暨南大学医学院组织胚胎学教研室,广东广州510632

出　　处：《中国医学影像技术》2012年第8期1493-1495,共3页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨彩色多普勒超声成像中甲状腺癌血管生成表现对诊断甲状腺结节的意义。方法回顾性分析37例经病理证实的结节性甲状腺肿合并甲状腺癌患者的彩色多普勒超声,比较良、恶性结节的血流分级、收缩期峰流速(PSV)、阻力系数(RI)和微血管密度(MVD)值。结果结节性甲状腺肿合并甲状腺癌患者中,恶性结节的血流分级多为Ⅱ级和Ⅲ级,处于较高水平;良性结节的血流分级主要集中在0级和Ⅰ级,处于较低水平(Z=3.74,P<0.001)。恶性结节的PSV[(41.30±19.99)cm/s]大于良性结节[(32.38±11.00)cm/s,t=2.37,P=0.02];恶性结节的MVD[(59.03±12.85)条/200倍镜]高于良性结节[(46.97±10.16)条/200倍镜](t=4.47,P<0.001)。结论恶性结节相对于良性结节具有较高的血流分级及PSV。彩色多普勒超声图像表现与肿瘤组织血管生成具有一致性。Objective To explore the features of angiogenesis in color Doppler ultrasound of thyroid nodules. Methods Color Doppler ultrasound of 37 cases of nodular goiter with thyroid cancer were analyzed retrospectively, and the blood flow grade, peak systolic velocity （PSV）, resistance index （RI） and microvascular density （MVD） for benign and malignant nodules were compared. Results The flow grade of benign nodules concentrated in low levels of 0and Ⅰ , hut the malig- nant nodules concentrated in high levels of Ⅱ and Ⅲ （Z=3.74, P〈0. 001）. PSV of malignant nodules （[41.30±19.99] cm/s） was larger than of benign ones （[32. 38±11.00] cm/s, t=2.37, P=0.02） ,and MVD of malignant nodules （59.03 ±12.85） was more than of benign＇s （46.97±10.16, t= 4.47, P〈O. 001）. Conclusion Compared with benign nodules, the malignant thyroid nodules have higher flow grade and PSV, of which ultrasonic manifestation and tumor angiogenesis has certain consistency.

关 键 词：甲状腺癌 恶性结节 血管生成 收缩期峰流速 阻力系数 

分 类 号：R736.1[医药卫生—肿瘤] R445.1[医药卫生—临床医学]