Turcot综合征合并肠道Burkitt淋巴瘤的临床病理观察  

Clinicopathologic features of Turcot syndrome associated with intestinal Burkitt lymphoma

作　　者：张淑红[1] 朱红[1] 周小鸽[1] 郑媛媛[1] 张彦宁[1] 陈光勇[1] 

机构地区：[1]首都医科大学附属北京友谊医院病理科,北京100050

出　　处：《诊断病理学杂志》2012年第4期270-273,共4页Chinese Journal of Diagnostic Pathology

摘　　要：目的探讨Turcot综合征合并肠道Burkitt淋巴瘤的临床病理特征。方法对1例Turcot综合征合并肠道Burkitt淋巴瘤进行光镜观察及免疫组化标记,并结合文献进行分析。结果患者先后行3次手术。第1次手术病理诊断为结肠多发性绒毛管状腺瘤;第2次手术病理诊断为脑间变性星形细胞瘤;第3次手术病理诊断为结肠多发性绒毛管状腺瘤及结肠Burkitt淋巴瘤。结论依靠临床病理特点,Turcot综合征的诊断相对容易,但其合并淋巴瘤十分罕见。二者之间是否存在一定的关系尚需进一步研究。Purpose To investigate the clinicopathologic characteristics of Turcot syndrome associated with intestinal Burkitt lymphoma.Methods One case of Turcot syndrome associated with intestinal Burkitt lymphoma was examined by microscopy and immunohistochemical staining,together with review of the literatures.Results The patient underwent three operations： the first pathological diagnosis was multiple tubulovillous adenomas of colon,the second was anaplastic astrocytoma of brain,and the third was multiple tubulovillous adenomas of colon associated with colonic Burkitt lymphoma.Conclusion Based on clinicopathologic characteristics,diagnosis of Turcot syndrome is relatively easy,but its association with lymphoma is very rare.Relationships between Turcot syndrome and lymphoma need further studies.

关 键 词：TURCOT综合征 BURKITT淋巴瘤 免疫组化 

分 类 号：R735.34[医药卫生—肿瘤]