藏药郎庆阿塔颗粒中挥发油成分研究  

Volatile Oil in Tibet Medicine Langqing Ata Granule

作　　者：鞠建明[1,2] 蔡雪萍[1] 江宝红[1] 黄一平[2] 

机构地区：[1]南京中医药大学药学院,南京210046 [2]江苏省中医药研究院,南京210028

出　　处：《中国实验方剂学杂志》2012年第15期105-108,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：江苏省社会发展项目(BS2007089);拉萨市科技局重大科技项目(200414)

摘　　要：目的:建立藏药郎庆阿塔颗粒中挥发油成分的定性定量方法。方法:采用气相色谱-质谱法对郎庆阿塔中挥发油成分进行定性鉴别,采用顶空气相色谱法对挥发油中的芳樟醇进行含量测定。结果:分离鉴定了郎庆阿塔挥发油中的36个化学成分,占挥发油总量的90%;芳樟醇在10.62～169.92μg峰面积积分值与进样量有良好的线性关系(r=0.999 9),平均加样回收率99.2%(n=6)。结论:所建方法简便、准确、可靠,可用于藏药郎庆阿塔颗粒中挥发油成分的质量控制。Objective： To develop the method for qualitative and quantitative determination of the volatile oil in Tibet medicine Langqing Ata granule.Method： All the volatile oil was identified by gas chromatography/mass spectrometry,and the content of linalool in volatile oil was determined by headspace gas chromatography.Result： Thirty-six compounds,about 90% of the total volatile oil,were separated and identified.The calibration curve of linalool was linear within the range of 10.62-169.92 μg,the correlation coefficient was 0.999 9,and the average recovery（n=6） was 99.2%.Conclusion： The established method is simple,accurate and reliable.It could be used for quality control of Tibet medicine Langqing Ata granule.

关 键 词：藏药郎庆阿塔 挥发油 气相色谱-质谱联用 芳樟醇 顶空气相色谱法 

分 类 号：R284.1[医药卫生—中药学]