宜宾地区18岁及以上人群重性抑郁障碍流行病学调查  

Epidemiological survey of severe depression among adults in Yibin city

作　　者：刘冬梅[1] 杨永和[1] 王志青[2] 向道华[1] 王世禹[1] 杨成敏[1] 李洪梅[1] 林俊[1] 

机构地区：[1]宜宾市康复医院,四川宜宾644002 [2]北京回龙观医院

出　　处：《中国预防医学杂志》2012年第7期507-510,共4页Chinese Preventive Medicine

基　　金：宜宾市精神病流行病学调查项目(编号200804002)

摘　　要：目的了解宜宾地区成年人群重性抑郁障碍的患病率及分布特点。方法采用多阶段分层整群抽样方法抽取宜宾地区≥18岁人群12 000人,用扩展的一般健康问卷(GHQ-12)筛查,将调查对象分为精神障碍高、中、低危险组,然后用美国精神障碍诊断与统计手册(DSM-IV)轴I障碍定式临床检查对不同比例的三组人群进行诊断检查。结果 11 227人完成了调查。调整后重性抑郁障碍的现患率为0.81%(95%CI为0.47%～1.38%),终生患病率为1.53%(95%CI为1.02%～2.31%)。重性抑郁障碍的终生患病率女性都高于男性(2.12%vs 0.80%,RR=2.64,RR的95%CI为1.89%～3.80%)。重性抑郁障碍的现患病率城市高于农村(1.48%vs 0.56%,RR=2.63,RR的95%CI为1.63%～4.34%)。在现患的重性抑郁障碍者中,43.61%的患者其日常功能受到重度损害,但仅有15.4%求助过医疗机构,仅7.7%求助过精神心理机构,仅2.6%接受过精神科住院治疗。结论宜宾地区重性抑郁障碍者日常功能高度受损害与其低求治率的现状应该引起相关卫生行政部门的高度重视。Objective To investigate the prevalence and geographical distribution of severe depression among adults in Yibin city.Methods A total of 12 000 subjects aged l8 and over were selected using multi-stage stratified cluster sampling in Yibin city.The participants were screened with the expanded version of General Health Questionnaire（GHQ-12） and classified as high,moderate or low risk of having schizophrenia based on the results,and were further diagnosed based on DSM-IV-TR（SCID-I/P）.Results There were 11,227 subjects who had completed the survey.The adjusted current prevalence of severe depression was 1.81%（95%CI：0.47%-1.38%）,while the lifetime prevalence was 1.53%（95% CI：1.02%-2.31%） which was significantly higher among women than that in men（2.12% vs 0.80%,RR=2.64,95% CI：1.89%-3.80%）.Meanwhile the current prevalence of severe depression among urban residents was also significantly higher than that in subjects from rural area（1.48% vs 0.56%,RR=2.63,95% CI：1.63%-4.34%）.There were 43.61% participants with current severe depression who could not function well for their daily lives,but only 15.4% had seeked for medical help,7.7% for psychological help and 2.6% treated psychiatrically in the hospital.Conclusions There are almost half of patients with severe depression whose daily lives are highly affected by their mental disorder,but only a small portion of them ask for medical help.More attention needs to be given to improve their mental health in Yibin city.

关 键 词：重性抑郁障碍 患病率 流行病学调查 

分 类 号：R749.4[医药卫生—神经病学与精神病学]