早产儿视网膜病变发病机制和治疗进展  

Research Progress in Pathogenesis and Treatment of Retinopathy of Prematurity

作　　者：杜安杰[1,2] 任兵[2] 

机构地区：[1]石河子大学医学院,新疆石河子832002 [2]解放军474医院全军眼科中心,乌鲁木齐830011

出　　处：《医学综述》2012年第14期2231-2233,共3页Medical Recapitulate

摘　　要：早产儿视网膜病变(ROP)是一种潜在的致盲性疾病,尽管及时的治疗,仍有许多患儿发展为视网膜脱离和视力丧失。目前较为有效的治疗方法是激光治疗,但激光治疗可破坏视网膜组织,导致视野缺损。目前针对眼部新生血管疾病投入了大量的研究,通过对血管生成相关因子的研究以寻找可能的方法抗新生血管生成,阻止ROP的发展。其中一些新的治疗干预措施已经进入临床试验阶段。Retinopathy of prematurity （ROP） is a potentially blinding disease of premature infants and despite timely treatment some infants develop retinal detachment and sight loss. Current treatment utilizes laser therapy which causes destruction of treated retinal tissue resulting in field loss. There is considerable research work ongoing on neovascular eye disease which is likely to result in antiangiogenic approaches that will arrest the development of ROP by angiogenesis-related factors. Some of these new therapeutic interventions have entered clinical trials.

关 键 词：早产儿视网膜病变 发病机制 视网膜新生血管 

分 类 号：R77[医药卫生—眼科]