以原发性静脉血栓形成为首发表现的恶性肿瘤22例分析  

Clinical Analysis of 22 Cases with Malignant Tumor for the First Signs of Constitutional Phlebothrombosis

作　　者：孙岩[1] 孔祥骞[1] 袁海[1] 吴学君[1] 金星[1] 

机构地区：[1]山东大学附属省立医院血管外科,济南250021

出　　处：《临床误诊误治》2012年第8期66-68,共3页Clinical Misdiagnosis & Mistherapy

基　　金：国家自然科学基金青年科学基金资助项目(81000186);山东大学研究生自主创新基金资助项目(yzc11081/21300071613081)

摘　　要：目的探讨以原发性静脉血栓形成为首发表现的恶性肿瘤临床特点,以及其对恶性肿瘤诊断的提示意义。方法回顾性分析我科2007年8月—2011年6月收治的22例以原发性静脉血栓形成为首发表现的恶性肿瘤的临床资料。本组均为中老年患者,均以肢体静脉血栓形成收住血管外科,4例合并肺栓塞。结果本组经规范抗凝治疗效果差,病情反复,均在住院或随访期间诊断恶性肿瘤,其中消化系统肿瘤8例,妇科肿瘤5例,血液系统、呼吸系统及胸部、泌尿系统肿瘤各3例。结论临床遇及原发性静脉血栓形成患者应积极查找病因,对规范抗凝治疗效果不佳者要警惕恶性肿瘤,及时完善肿瘤相关检查,以早期诊治。Objective To explore the clinical characteristics of malignant tumor for the first signs of constitutional phlebothrombosis and the significance for diagnosing malignant tumor. Methods Retrospective analysis of 22 cases with malignant tumor for the first signs of constitutional phlebothromhosis during August 2007 and June 2011 were conducted. These patients were elderly age group with deep vein thrombosis in upper or lower limbs and 4 of them were cmubined with pulmonary embolism. Results The normative anticoagulant therapy for these patients was poor with repeated relapses. All of them were diagnosed as having malignant tumor during hospitalization or follow up, including 8 patients with digestive system cancer, 5 patients with gyneeologic neoplasms, 3 patients with neoplasms of hematological system, neoplasms of respiralory system, chest cancer and urlogie neoplasms respective- ly. Conclusion Greater efforts shouht be made to find the cause of primar7 venous thrombosis and beware of the oeeurrenee of raalignaut tumors for ineftetive patients with standard anticoagulant therapy, and relevant exmninations of ttmor ean improve the early diagnosis rate.

关 键 词：静脉血栓形成 肿瘤 并发症 

分 类 号：R730.5[医药卫生—肿瘤]