多学科合作切除颅底沟通性肿瘤  

Multidisciplinary collaberation for surgical treatment of skull base tumors with intra and extra - cranial involvement

作　　者：伊志强[1] 鲍圣德[1] 李良[1] 张家涌[1] 肖水芳[2] 秦永[2] 郭传瑸[4] 张建国[4] 聂红平[3] 

机构地区：[1]北京大学第一医院神经外科,100034 [2]北京大学第一医院耳鼻喉科,100034 [3]北京大学第一医院眼科,100034 [4]北京大学口腔医院颌面外科

出　　处：《中华神经外科杂志》2012年第8期768-771,共4页Chinese Journal of Neurosurgery

基　　金：基金项目：首都医学发展科研基金（2009-1040）

摘　　要：目的探讨颅内外沟通肿瘤多学科合作的手术方式，提高手术疗效。方法回顾性分析经多学科合作切除的78例颅底沟通肿瘤，分析肿瘤起源和侵及范围与手术入路的关系，探讨手术并发症及其防治。结果肿瘤全切除48例，次全切除25例，部分切除5例。36例术后出现并发症，无手术相关死亡。结论多学科合作切除颅底沟通肿瘤可提高手术疗效。肿瘤的起源和侵及范围是选择手术人路的重要依据。血管、脑神经损伤，脑脊液漏及颅内感染是主要的并发症。Objective To study the multidisciplinary collaberation for surgical treatment of skull base tumors with intra and extra- cranial involvement. Methods 78 cases of skull base tumors with intra and extra - cranial involvementwere analyzed retrospectively. The relationship between surgical approaches and the orion and extension of the tumors was analyzed. The main complications and avoidance was discussed. Results Total tumor removal was performed in 48 cases, subtotal in 25 and partial in 5. The operation- related complications occurred in 36 patients without death. Conclusions Muhidisciplinary collaboration benefits the surgical therapy for skull base tumor with intra and extra - cranial involvement. The origin and extension of the tumor is the most important consideration in determining the surgical approaches. The injury of blood vessel and cranial nerves, cerebrospinal fluid leakage and intracranial infection are the main operative complications.

关 键 词：颅底肿瘤 手术 多学科合作 

分 类 号：R739.41[医药卫生—肿瘤]