原发性输卵管癌45例临床分析  

Primary Fallopian Tube Carcinoma:A Clinical Analysis of 45 Patients

作　　者：饶爱勤[1] 宋磊[2] 陈劲松[1] 周宁[2] 吴晓玲[1] 

机构地区：[1]解放军第187医院,海南海口571159 [2]解放军总医院,北京100853

出　　处：《实用妇产科杂志》2012年第7期559-561,共3页Journal of Practical Obstetrics and Gynecology

摘　　要：目的:探讨原发性输卵管癌的临床表现及病理特征、诊治方法,以期提高对该病的认识。方法:回顾性分析我院2000～2010年收治的45例原发性输卵管癌患者的临床情况及诊治结果。结果:45例患者平均年龄56.9岁,30例(66.7%)为绝经后妇女。最常见的临床表现依次为盆腔肿块40例(88.9%),阴道排液13例(28.9%),腹胀10例(22.2%),腹痛9例(20.0%),异常阴道流血伴流液7例(15.6%),便秘2例(4.4%)。超声检查发现40例(88.9%)有盆腔肿块;32例行血清癌抗原125(CA125)水平测定,26例(81.3%)高于35U/ml。Ⅰ～Ⅳ期患者的5年生存比例分别为:Ⅰ期66.7%、Ⅱ期50.0%、Ⅲ期36.0%,Ⅳ期0。满意的肿瘤细胞减灭术患者较缩瘤术患者存活时间长。结论:原发性输卵管癌恶性程度高,临床表现多样且缺乏特异性,很少能在术前明确诊断。超声检查及CA125检测有助于诊断。手术是主要治疗手段。Objective： To analyze the clinic pathologic features and treatment of primary fallopian tube carcinoma（PFTC）. Methods： forty-five patients with PFTC treated at our hospital were retrospectively ana- lyzed. Results：The mean age of these patients was 56.9 years. Thirty patients（66.7% ）were menopausal women. The most common clinical manifestation was pelvic mass（40,88.9% ）, followed by vaginal dis- charge（ 13,28.9% ）, abdominal distension （ 10, 22.2% ）, abdominal pain （ 9,20, 0% ）, abnormal vaginal bleeding （7,15.6%）, astriction （2, 4.4% ）. 88.9% patients were detected with pelvic mass by sonography. The sera CA125 was higher than 35 U/ml in about 81.3% （26/32） of patients. 5 year survival rates of [ - stages were. ] 66.7%, Ⅱ 50.0%, Ⅰ1136.0%, Ⅳ0. Optimal cytoreductive surgery could achieve a long sur- vival time. Conclusions：PFTC is a rare gynecologic malignancy that has various and nonspecific presenta- tions. Preoperative diagnosis of the disease is extremely rare. Sonography and CA125 may help to the early diagnosis of primary fallopian tube carcinoma. Surgery are the main therapies for this disease.

关 键 词：原发性输卵管癌 超声检查 癌抗原125 

分 类 号：R737.32[医药卫生—肿瘤]