中年妇女年龄、月经状态、体重指数及体力活动对机体组成及脂肪分布的影响  

Influence of age,menopause status,body mass index and physical activity on body composition and body fat distribution in midlife women

作　　者：魏代敏[1] 郁琦[1] 张颖[1] 陈凤领[1] 

机构地区：[1]中国医学科学院,北京协和医学院,北京协和医院妇产科,北京100730

出　　处：《生殖医学杂志》2012年第4期308-313,共6页Journal of Reproductive Medicine

摘　　要：目的研究中年妇女年龄、月经状态、体重指数(body mass index,BMI)及体力活动对机体组成及脂肪分布的影响。方法横断面收集于北京协和医院体检中心体检的健康妇女,利用经过效度和信度检验的国际体力活动问卷短卷中文版调查研究对象的体力活动情况,利用双能X线吸收法(DEXA)测定机体组成及脂肪分布情况。结果共收集到162例妇女资料,年龄40～62岁、(52.81±5.31)岁。多元线性回归分析结果显示,全身脂肪组织百分比与BMI(标准化偏回归系数b=0.70)、月经状态(b=0.19,生育期赋值1,绝经过渡期赋值2,绝经后赋值3,下同)呈正相关,而与体力活动能量消耗呈负相关(b=-0.17),回归方程的决定系数R^2=0.55。全身无脂肪组织含量(fat-free tissue)与BMI呈正相关(b=0.61)、与月经状态呈负相关(b=-0.14),回归方程的决定系数R^2=0.39。躯干脂肪/全身脂肪比值与BMI(b=0.32)、月经状态(b=0.30)呈正相关,回归方程的决定系数R^2=0.20。校正了BMI、月经状态及体力活动的影响后,年龄与全身脂肪组织百分比、全身无脂肪组织含量、躯干脂肪/全身脂肪比值均无明显相关性。结论月经状态对机体组成及脂肪分布具有独立影响,随着生殖衰老的进展,脂肪组织增加且趋于中心性分布,机体无脂肪组织含量降低。而年龄本身与机体组成及脂肪分布无直接关系。中年妇女应增加体力活动,保持适当的体重以降低绝经对脂肪组织所造成的不利变化。Objective： To investigate the influence of age, menopause status, body mass index （BMI） and physical activity on body composition and body fat distribution in Chinese midlife women. Methods： The healthy women who underwent anniversary health checkup in Peking Union Medical College Hospital were recruited cross-sectionally. The level of physical activity was determined via International Physical Activity Questionare-Short in Chinese Version. The body composition and fat distribution were measured by dual-energy X-ray absorptiometry. Results： A total of 162 women with average age 52 years （40-62 years） were collected. Multiple linear regression analysis was performed to test the relationship between age, menopause status, BMI and physical activity and parameters of body composition ~ body fat distribution. The total fat tissue percentage was positively associated with BMI （standardized partial regression coefficient： b = 0. 70）, menopause status （b=0.19, grading variable 1, 2, 3） were assigned to represent for reproductive group,menopausal transition group and postmenopausal group, respectively, and negatively associated with physical activity energy expenditure （b=--0.17） with model determination coefficient 0.55. Total body fat-free mass was positively associated with BMI （b = 0.61）, negatively associated with menopause status （b=--0.14） with model determination coefficient 0.39. The ratio of trunk fat tissue/total body fat tissue was positively related with BMI （b = 0. 32） and menopause status （b = 0. 30） with model determination coefficient 0.20. After adjusted the effects of BMI, menopause status and physical activity, age was not significantly related with total fat tissue percentage, body fat-free mass, nor ratio of trunk fat tissue/total body fat tissue. Conclusions： Menopause impact body composition and body fat distribution independently. During the process of female reproductive aging, body fat tissue mass increases and becomes more susceptible to distribu

关 键 词：绝经 体力活动 机体组成 脂肪分布 

分 类 号：R[医药卫生]