Mollaret脑膜炎的临床和脑脊液特点(附1例报告)  

Clinical and cerebrospinal fluid pathological features of Mollaret meningitis

作　　者：孙琦[1] 陈道文[1] 王立[1] 

机构地区：[1]南京医科大学附属脑科医院神经内科,210029

出　　处：《临床神经病学杂志》2012年第4期288-290,共3页Journal of Clinical Neurology

摘　　要：目的探讨Mollaret脑膜炎(MM)的临床与脑脊液(CSF)特点。方法回顾性分析1例MM患者的临床资料。结果本例男,26岁,急性起病,以头痛、发热、恶心、呕吐及脑膜刺激征为主要表现,先后复发4次。每次复发时的症状及体征基本相似,间歇期完全正常。腰穿CSF检查:白细胞81×106/L,以淋巴细胞为主(0.89),蛋白含量0.71 g/L,氯化物116 mmol/L,IgG 79.5 mg/L。经对症治疗3周基本痊愈。结论MM以头痛、发热、恶心、呕吐及脑膜刺激征为主要临床表现,可反复发作,但预后良好。CSF有细胞数和蛋白增高,以淋巴细胞、单核细胞为主,疾病初期可找到特征性Mollaret细胞。Objective To discuss the clinical and cerebrospinal fluid （CSF） features of Mollaret meningitis （MM）. Methods The clinical data of 1 MM patient were analyzed retrospectively. Results The patient was man, 26 years old, and he was acute onset. The main clinical manifestations were headache, fever, nausea, vomit and meningeal irritation sign. And he recurred 4 times successively. The symptoms and signs were basically similar in recrudescence, and the dormant period was normal. The lumbus puncture CSF examination showed that leucocyte was 81 × 10^6/L, lymphocyte was the predominant （0.89） , protein level was 0.71 g/L, chloride was 116 retool/L, IgG was 79.5 mg/L. After 3 weeks of the symptomatic treatment, the patient was basic cured. Conclusions The main clinical performances of MM are headache, fever, nausea, vomit and meningeal irritation sign, and repeated attacks, but the prognosis is good. The cell number and protein level are increased in CSF, lymphocyte and monocyte are the predominant. The characteristic Mollaret cell can be found in the early stage of disease.

关 键 词：MOLLARET脑膜炎 脑膜刺激征 脑脊液 

分 类 号：R742.89[医药卫生—神经病学与精神病学]