陆眠宁Ⅱ复合麻醉在小型猪牙种植实验中的效果观察  

Observation of Lumianning Ⅱ Compound Anesthetic Effects in Dental Implant Experiment on Minipigs

作　　者：王利民[1] 郑园娜[2] 杨国灵[1] 谷志远[2] 

机构地区：[1]中国人民解放军第一一七医院口腔科,浙江杭州310004 [2]浙江中医药大学口腔医学院,浙江杭州310006

出　　处：《中国血液流变学杂志》2012年第2期212-213,263,共3页Chinese Journal of Hemorheology

基　　金：浙江省自然科学基金资助项目（Y2101440）

摘　　要：目的 探索一种适合小型猪牙种植实验的麻醉方法。方法 小型猪12只，随机均分为2组，单纯麻醉组采用陆眠宁Ⅱ0．2mL／kg肌肉注射，复合麻醉组采用陆眠宁Ⅱ联合氯胺酮0．2mL／kg肌肉注射（按1：1混合）。观察麻醉显效时间、维持时间、苏醒时间并记录麻醉过程中体温、呼吸、心跳变化。结果 陆眠宁Ⅱ、氯胺酮复合麻醉组在麻醉显效时间、维持时间上优于陆眠宁Ⅱ单纯麻醉组，复合麻醉可以提高陆眠宁Ⅱ的麻醉效果，且用量较小，对心血管、呼吸无明显抑制。结论 陆眠宁Ⅱ、氯胺酮复合麻醉是小型猪牙种植实验理想的麻醉方法。Objective To explore a kind of anesthetic methods which is suitable for experimental dental implantation on minipigs.Methods Twelve minipigs undergoing experimental dental implantation were divided randomly into two groups.In one group,animals were induced with intramuscular Lumianning II injection in a dose of 0.2mL/kg.While in the other, l：l mixture of Lumianning Ⅱ and ketamine was adopt in the same way of intramuscular injection.The anesthesia induction time,maintenance time,analepsia time,body temperature,breathing frequency and heart rate during the anesthesia period were observed and recorded in both two groups.Results It was found that the anesthesia induction time and maintenance time of Lumianning I/ combined with ketamine were significantly superior to Lumianning Ⅱ alone.The combined anesthetization could improve the effect of Lumianning Ⅱ treatment,and did not interfere with respiration and circulatory system during the,anesthesia process.Conclusion Lumianning II combined with ketamine was considered as a satisfactory method to anesthetize minipigs during the experimental dental implantation.

关 键 词：小型猪 牙种植 陆眠宁Ⅱ 麻醉 

分 类 号：R782.12[医药卫生—口腔医学]