超声造影在肝癌射频消融治疗前后的临床价值研究  

Clinical Value of Contrast-enhanced Ultrasonography in Liver Cancer before and after Radiofrequency Ablation

作　　者：黄蕊[1] 高岩[1] 王静[1] 谢蠡[1] 

机构地区：[1]哈尔滨医科大学第一临床医学院门诊超声科,黑龙江哈尔滨150001

出　　处：《现代生物医学进展》2012年第23期4451-4453,共3页Progress in Modern Biomedicine

摘　　要：目的:探讨实时超声造影(contrast-enhanced ultrasonography,CEUS)在原发性肝癌射频消融(radiofrequency ablation,RFA)微创介入前后治疗临床应用价值的研究。方法:通过分析139例肝癌患者175个病灶在超声引导下射频消融(RFA)治疗,对病灶数量、大小、边界、内部回声、造影剂灌注情况进行对比分析,及治疗后与增强CT结果进行对照。结果:射频消融前,超声造影显示82个病灶表现为动脉早期抱球状、弥漫或轻度增强;治疗1-3个月后超声造影判定89.1%(156/175)的病灶达到完全消融,10.9%(19/175)的病灶消融不完全;增强CT判定84.6%(148/175)的病灶达到完全消融,15.4%(27/175)的病灶消融不完全,治疗后超声造影检查结果与CT增强检查结果一致,两者在病灶残留复发的敏感性、特异性、准确性等方面比较无显著性差异,P>0.01。结论:实时超声造影(CEUS)能准确判断RFA对肿瘤消融的范围及程度,是一种指导治疗,判定治疗后疗效的新方法,在原发性肝癌(RFA)微创介入治疗中具有很高的临床应用价值。Objective： This article is aimmed to explore the clinical value of contrast-enhanced ultrasonography by examing before and atter the minimally invasive interventional treatment contrast-enhanced ultrasonography on radiofrequency ablation to cure the disease of Hepatocellular Carcinoma. Methods： To retrospect the 175 cases of infection belonging to 139 Liver cancer patients respectively, which was under ultrasound guidance to do radiofrequency ablation, to review the ultrasonic imaging before and after the theraphy, the number, size, border, internal echo and medium infusion are analyzed by comparison of infection. And the CT scanning are intesified in order to be compared further more. By analyzing 139 cases of liver lesions in 175 patients with ultrasound-guided radiofrequency ablation （RFA） treatment, the lesion number, size, border, internal echo, contrast agent perfusion were compared, and the treatment results were compared with contrast-enhanced CT. Real-time ultrasound imaging （CEUS） can accurately determine the scope of RFA ablation of tumors and extent of treatment is a guide to determine the efficacy of new treatment methods in primary liver cancer （RFA） in the minimally invasive treatment of high clinical application value.

关 键 词：射频消融 肝癌 实时超声造影 价值 

分 类 号：R735.7[医药卫生—肿瘤]