鉴别诊断胸腹腔积液的实验诊断项目的选择  

Project selection of experimental diagnosis for differential diagnosis of splanchnocoele effusion

作　　者：赵维川[1] 武英伟[1] 李庆红[1] 卢冬梅[1] 关慧臻[1] 吕喜英[1] 薛承岩[1] 

机构地区：[1]承德医学院附属医院检验科,河北承德067000

出　　处：《国际检验医学杂志》2012年第10期1185-1186,共2页International Journal of Laboratory Medicine

摘　　要：目的探讨同型半胱氨酸(HCY)、癌胚抗原(CEA)、C-反应蛋白(CRP)、β2-微球蛋白(β2-MG)和腺苷脱氨酶(ADA)联合检测在胸腹腔积液诊断中的价值。方法分别检测50例恶性胸腹腔积液(恶性组)、40例结核性胸腹腔积液(结核组)和40例感染性胸腹腔积液(炎症组)中HCY、CEA、CRP、β2-MG和ADA含量,并进行比对分析。结果恶性组胸腹腔积液中HCY、CEA含量明显高于结核组和炎症组(P<0.05),CRP含量明显低于结核组和炎症组(P<0.05),β2-MG、ADA含量明显低于结核组(P<0.05)。结论联合检测胸腹腔积液中HCY、CEA、CRP、β2-MG和ADA含量在胸腹腔积液鉴别诊断中具有重要的临床实用价值。Objective To explore the value of combined detection of homocysteine（HCY）,carcinoembryonic antigen（CEA）,C-reactive protein（CRP）,β2-microglobulin（β2-MG） and adenosine deaminase（ADA） for differential diagnosis of splanchnocoele effusion.Methods Contents of HCY,CEA,CRP,β2-MG and ADA were determined and compared in 50 patients with malignant splanchnocoele effusion（malignant group）,40 patients with tuberculous splanchnocoele effusion（tuberculosis group） and 40 patients with inflammatory splanchnocoele effusion（inflammatory group）.Results The contents of HYC and CEA in malignant group were significantly higher than in tuberculosis and inflammatory group（P〈0.05）,but that of CRP was obviously lower（P〈0.05）,while those of β2-MG and ADA were obviously lower than in tuberculosis group（P〈0.05）.Conclusion Combined determination of HCY,CEA,CRP,β2-MG and ADA might be with significant clinical significance for the differential diagnosis of splanchnocoele effusion.

关 键 词：半胱氨酸 癌胚抗原 C反应蛋白质 Β2微球蛋白 腺苷脱氨酶 胸腔积液 腹水液 诊断 鉴别 

分 类 号：R730.4[医药卫生—肿瘤]