RNase9蛋白的抗菌活性及在炎性附睾组织中的表达  

Anti-bacteria activity of RNase9 protein and its expression in epididymitis

作　　者：刘杰[1] 孙成铭[1] 张成林[1] 张守信[1] 

机构地区：[1]山东省烟台毓璜顶医院生物芯片实验室,264000

出　　处：《国际检验医学杂志》2012年第10期1193-1193,1195,共2页International Journal of Laboratory Medicine

摘　　要：目的探讨附睾特异表达RNase9蛋白活性及其在炎性附睾组织中的表达情况。方法主要通过体外实验研究其抗菌活性,通过Western blot和荧光定量聚合酶链反应(FQ-PCR)分析正常附睾组织和炎性附睾组织中RNase9蛋白表达情况。结果 RNase9蛋白具有抗菌活性;在炎性附睾组织中RNase9蛋白表达水平升高。结论 RNase9蛋白可能参与附睾炎症过程。Objective To study the activity of RNase9 protein and its expression in the tissue of epididymitis.Methods Anti-bacteria activity of RNase9 protein was detected by using in vitro analysis.Western bolt and fluorescent quantitation polymerase chain reaction（FQ-PCR） were performed to analyze the expression of RNase9.Results The RNase9 protein was confirmed to be with anti-bacterial activity and highly expressed in tissue of epididymitis.Conclusion RNase9 protein might participate in the development of epididymitis.

关 键 词：附睾炎 蛋白 RNase9 抗菌 

分 类 号：R363[医药卫生—病理学]