嗜铬细胞瘤的^(131)I-MIBG显像诊断与病理对照分析  

Comparision of ^(131)I-MIBG imaging with pathology in phaeochromocytoma

作　　者：裘汉璋[1] 李自成[1] 巫少荣[1] 

机构地区：[1]暨南大学医学院第一附属医院心内科,广州510630

出　　处：《临床内科杂志》2000年第4期219-220,共2页Journal of Clinical Internal Medicine

摘　　要：目的　评价 1 31 I-间位碘卞胍 (1 31 I- MIBG)显像对嗜铬细胞瘤的诊断价值。方法　观察2 1例经病理证实为嗜铬细胞瘤患者的 B超、CT、尿香草基杏仁酸 (VMA)和 1 31 I- MIBG显像结果 ,并与病理结果进行回顾性对照分析。结果　 B超、CT、尿 VMA对嗜铬细胞瘤的检出率分别为81%、90 .5 %和 6 8.4% ,1 31 I- MIBG显像对嗜铬细胞瘤的检出率达 10 0 % ,1 31 I- MIBG显像的敏感性、特异性和准确性最高。结论　 B超和 CT未发现病变 ,疑有肿瘤异位时 1 31 I-Objective To evaluate the clinical value of iodine 131 labeled metaiiodo benzylguanidine ( 131 I MIBG) imaging in diagnosis of phaeochromocytoma.Methods B model ultrasonogram,CT,urinary vanillylmandelic acid (VMA) and 131 I MIBG imaging were carried out in 21 patients with phaeochromocytoma proven by pathology and their outcomes were analysed. retrospectively.Results The detective rate of 131 I MIBG imaging was 100% in diagnosis of phaeochromocytoma , while those of B model ultrasonogram,CT,urinary VMA were 81%,90.5%,68.4% respectively.The sensitivity,specificity,accuracy of 131 I MIBG imaging were highest in diagnosis of phaeochromocytoma . Conclusion 131 I-MIBG imaging was the first diagnostic method of phaeochromocytoma . [

关 键 词：嗜铬细胞瘤 诊断 碘131 间位碘卞胍显像 病理学 

分 类 号：R736.6[医药卫生—肿瘤]