急性脑梗死患者治疗前后临床血清学变化  

Changes of Blood Serum in Acute Cerebral Infarction After Treatment

作　　者：石瑾[1] 李蔷[1] 尹久红[1] 荣蓉[1] 周梅[1] 温庆祥[1] 石文静 

机构地区：[1]首都医科大学附属北京中医医院,北京100010 [2]清华大学第一附属医院北京华信医院,北京100016

出　　处：《标记免疫分析与临床》2012年第4期229-230,共2页Labeled Immunoassays and Clinical Medicine

摘　　要：目的探讨急性脑梗死患者治疗前后血清高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、血浆血栓素B2(TXB2),6-酮-前列腺素F1α(6-K-PGF1α)、甘油三脂(TG)、β脂蛋白(β-LP)的变化。方法对94例急性脑梗死患者(男58例,女36例),用放射免疫和生化方法检测血样本中HDL、LDL、TXB2、6-K-PGF1α、TG、β-LP的含量。结果急性脑梗死患者治疗后HDL、6-K-PGF1α浓度明显升高(P<0.05),LDL、TG、β-LP、TXB2浓度显著降低(P<0.01)。结论急性脑梗死患者治疗后血液的高凝状态明显改变,血脂降低。Objective To investigate the changes Of serum of HDL, LDL, TXB2,6-K-PGF1α, TG and β-LP in acute cerebral infarction after treatment. Method The serum levels of HDL, LDL, TXB2,6- K- PGF1α, TG and β-LP in 94 acute cerebral infarction patients were detected by RIA and biochemistry assay respectively. Results The results showed that the serum HDL and 6-K-PGF1α levels in acute cerebral infarction patients were increased （P 〈 0.05 ）, while the serum levels of LDL, TG, β-LP and TXB2 were decreased （P 〈 0.01 ） after treatment. Conclusion The Hypercoagulable state and blood fat index in acute cerebral infarction after treatment could improve obviously.

关 键 词：急性脑梗死 放射免疫 生化 

分 类 号：R743.33[医药卫生—神经病学与精神病学]