食管基底细胞样鳞癌的临床病理特点及疗效分析  

Analysis of the Clinical Pathological Characteristics and Efficacy in Esophageal Babasaloid Squamous Cell Carcinoma

作　　者：白亚军[1] 牛育鸿[1] 何敏[1] 党凯[1] 邱小刚[1] 白有士[1] 

机构地区：[1]延安大学西安创新学院,陕西西安710100

出　　处：《肿瘤药学》2012年第4期290-292,共3页Anti-Tumor Pharmacy

摘　　要：目的探讨食管基底细胞样鳞癌(basaloid squam ous cell carcinom a of the esophagus,BSC)患者的临床病理特点和临床疗效。方法对我院2008年1月至2011年3月收治的458例食管基底细胞样鳞癌患者的资料做回顾性分析,总结BSC的病理特点,并比较其与其他类型食管鳞癌(ESC)的病理特征和临床疗效的差异。结果 BSC患者的平均年龄和肿瘤侵犯周围脏器的发生率均明显高于ESC患者(P<0.05);两组患者手术成功率均是100%;BSC组和ESC组的平均生存时间分别是(17.5±10.3)月、(33.4±15.5)月,ESC组明显高于BSC组(P<0.05)。结论食管基底细胞样鳞癌在临床上具有与传统食管鳞癌不同的生理病理特点,采用根治手术联合化疗治疗食管基底细胞样鳞癌的临床效果较传统食管鳞癌差。Objective To investigate the clinical pathological characteristics and clinical efficacy in esophageal basaloid squamous cell carcinoma （BSC）. Methods A retrospective analysis of 458 cases of esophageal BSC patients from January 2008 to March 2011 was performed to summarize the pathological characteristics ofBSC, and compare the physiological characteristics and clinical efficacy with other types of esophageal squamous cell carcinoma （ESC）. Results The average age and incidence rate of tumor invasion of surrounding organs of BSC patients were both significantly higher than those in ESC patients （P〈0.05）. The surgical success rate in both groups was 100%. The average survival time of ESC group which was （33.4 ±15.5） months was significantly higher than that of BSC group which was （17.5±10.3） months （P〈 0.05）. Conclusion There were significant differences in physiological and pathological characteristics between ESC group and BSC group. Treatment with radical operation plus chemotherapy on BSC was no more effective than on ESC.

关 键 词：食管癌 基底细胞样鳞癌 病理特点 疗效 

分 类 号：R735.1[医药卫生—肿瘤]