卤素离子-富马酸酮替芬-联吡啶钌体系电化学发光的研究及应用  

The effect of halide ions on the electrogenerated chemiluminescence emission intensity of ketotifen fumarate-ru(bpy)_3^(2+) system at an Au electrode

作　　者：李利军[1] 邓春燕[1] 高文燕[2] 吴美艳[1] 胡大春[1] 李彦青[1] 黄文艺[1] 

机构地区：[1]广西工学院生物与化学工程系,柳州545006 [2]广西大学化学化工学院,南宁530004

出　　处：《分析试验室》2012年第9期21-25,共5页Chinese Journal of Analysis Laboratory

基　　金：桂科自(0832062)项目;国家自然科学基金(20665001)资助

摘　　要：在卤素离子存在下,考察了富马酸酮替芬-Ru(bpy)32+体系在金电极上的电化学及其发光行为。结果表明:Br-对富马酸酮替芬-Ru(bpy)32+体系在金电极上发光行为具有显著的促进和增敏作用。据此,建立了一种高效、简便的富马酸酮替芬检测的新方法。在最佳实验条件下,富马酸酮替芬在1.0×10-4～1.0×10-7mol/L浓度范围内与相对发光强度呈线性关系,回归方程为I(counts)=1.73×108c+188.15(R2=0.9989),检出限(S/N=3)为4.29×10-8mol/L,连续平行测定富马酸酮替芬溶液(1×10-5mol/L)6次,发光强度的RSD为4.7%。回收率在99.5%～105.0%之间,RSD为2.3%(n=5)。该方法用于实际样品的测定,结果满意。The electrochemical and electrogenerated chemiluminescence （ECL） behaviours of tris （2, 2＇ bipyridyl） ruthenium （II）-ketotifen fumarate system at the Au electrode were studied in the presence of halide ions. An enhanced electrochemical activity and ECL response were exhibited in the presence of Br . Based on this, a new ECL method was established for the determination of ketotifen fumarate. Under the optimum experimental conditions, the ECL intensities had good linear relationship with the concentration of the ketotifen fumarate in the range of 1.0 ~ 10-4 ~ 1.0 ~ 10-7 mol/L, and the linear regression equation was obtained as follows ： I（counts） = 1.73 ＊ 10% ＋ 188.15 （ R2 = 0. 9989）. The detection limit （ S/N = 3 ） was 4. 29 ＊ 10 -s mol/L. The RSD for 6 times determination of 1.0 ~ 10-5 mol/L ketotifen fumarate was 4.7%. The results of recovery were between 99.5% and 105.0%, the RSD for 5 times was 2.3%. This proposed method showed high selectivity and sensitivity, and the treatment method of the sample was simple.

关 键 词：卤素离子 富马酸酮替芬 联吡啶钌 电化学发光 金电极 

分 类 号：O657.1[理学—分析化学]