岩斜区脑膜瘤术后预后相关因素分析  

Analysis of the Related Factors Affecting Prognosis after Resecting Petroclival Meningiomas

作　　者：魏攀[1] 张跃康[2] 庄进学[1] 陈登奎[1] 陶传元[1] 薛峰[1] 张炜[1] 李海龙[1] 郑小强[1] 

机构地区：[1]解放军452医院神经外科,成都610021 [2]四川大学华西医院神经外科

出　　处：《华西医学》2012年第7期997-1000,共4页West China Medical Journal

摘　　要：目的探讨影响岩斜区脑膜瘤(PCM)预后的相关因素。方法回顾分析解放军452医院2005年9月-2009年6月及四川大学华西医院1999年9月-2009年2月110例患者的临床资料及随访结果,通过单因素生存分析及Cox比例风险模型分析探讨影响PCM预后的相关因素。结果单因素生存分析发现8种相关因素影响PCM患者的预后,但Cox多因素分析仅发现脑干T2像高信号(OR=5.54,P=0.012)、肿瘤侵入脑干(OR=5.10,P=0.034)、病理高级别(OR=4.03,P=0.011)这3种因素有统计学意义。结论脑干T2像高信号、肿瘤侵入脑干、病理高级别可影响岩斜区脑膜瘤患者的预后。Objective To investigate the factors influencing the prognosis after resection of petroclival meningiomas （PCMs）. Methods The clinical data and follow-up results of 110 patients with PCMs treated in West China Hospital from September 1999 to February 2009 and in our hospital from September 2005 to June 2009 were reviewed. The factors affecting prognosis of PCMs were explored by using single-factor log-rank test and Cox proportional hazards model. Results Univariate survival analysis by log-rank test found that eight factors were related to the prognosis of patients with PCMs, but Cox multivariate analysis showed only 3 of them had statistical significance including a high T2 signal of the brain stem （OR=5.54, P=0.012）, invasion of the tumor into the brain stem （OR=5.10, P=0.034）, and high-grade pathologic types （OR=4.03, P=0.011）. Conclusion High signal in T2 weighed image of the brain stem, tumor invading brain stem and the pathological types of high grade are the three main factors influencing the prognosis of PCMs.

关 键 词：岩斜区 脑膜瘤 预后 相关因素 生存分析 

分 类 号：R739.45[医药卫生—肿瘤]