倍他司汀联合丹参治疗椎-基底动脉供血不足的疗效观察  

Clinical Observation on Vertebro-basilar Insufficiency Treated with Betahistine and Salvia miltiorrhiza

作　　者：魏九金[1] 刘景英[1] 

机构地区：[1]广东省东莞市桥头医院,广东东莞523523

出　　处：《赣南医学院学报》2012年第3期368-369,共2页JOURNAL OF GANNAN MEDICAL UNIVERSITY

摘　　要：目的:观察倍他司汀联合丹参治疗椎-基底动脉供血不足的疗效。方法:119例椎-基底动脉供血不足(VBI)患者分为2组,对照组59例,给予丹参注射液20 mL加入0.9%氯化钠注射液250 mL静脉滴注,1次/d,疗程10 d。治疗组60例,在对照组治疗的基础上加倍他司汀口服液20 mg,2次/日。治疗前后进行经颅多普勒(TCD)检查及治疗后临床疗效评定。结果:经过10 d治疗后治疗组总有效率91.1%,优于对照组为78.0%。差异有统计学意义(P<0.05);TCD显示治疗组收缩期血流峰值流速(Vp)改善优于对照组。结论:倍他司汀口服液联合丹参注射液治疗VBI效果好,值得临床推广应用。Objective：To observe the clinical effect on vertebro-basilar insufficiency treated with Betahistine and Salvia mihiorrhiza. Methods： 119 cases of vertebral-basilar insufficiency （VBI） were divided into two groups, Control Group and Treatment Group. 59 patients in the Control Group were given Salvia mihiorrhiza injection 20 mL 0.9% sodium chloride injection 250 mL, intravenous drip per day and 10 days as a course ;60 patients in the Treatment Group were given Salvia miltiorrhiza injection 20 mL 0.9% sodium chloride injection 250 mL, intravenous drip and Betahistine oral liquid 20 mg,2 times/day. Patients of the two groups were examined by transcranial Doppler （TCD） before and after treatment, and clinical assessment were compared after treatment. Results：After treatment, the total effective rate was 91.1% in the Treatment Group and 78.0% in the Control Group, with significantly difference （ P 〈 0.05 ） ; The peak values of blood flow velocity of vertebro-basilar was significantly better in the Treatment Group than that of the Control Group. Conclusion： This combination use to treat VBI was effective. It is worthy of clinical application.

关 键 词：倍他司汀 椎-基动脉供血不足 经颅多普勒 

分 类 号：R743.9[医药卫生—神经病学与精神病学]