胆管乳头状瘤临床分析及文献研究  

Clinical Analysis and Literature Review of Biliary Papillomatosis

作　　者：张迎春[1] 麻树人[1] 张宁[1] 潘汝明[1] 赵云峰[1] 赵志峰[1] 

机构地区：[1]沈阳军区总医院内窥镜科,沈阳110016

出　　处：《解放军医药杂志》2012年第8期32-35,共4页Medical & Pharmaceutical Journal of Chinese People’s Liberation Army

摘　　要：目的探讨胆管乳头状瘤的临床表现、病理特点、诊断及治疗方法。方法对我院1994—2011年确诊的7例胆管乳头状瘤的临床资料进行回顾性分析,同时检索中国期刊全文数据库同期有关胆管乳头状瘤的报道11篇文献29例患者,并进行分析。结果胆管乳头状瘤临床表现为腹痛占91.7%,腹痛伴有黄疸占72.2%;实验室检查血清总胆红素升高占69.4%,CA19-9升高占37.5%;影像学提示胆总管扩张占88.9%,组织学检查癌变占30.6%,随访28例,复发率为53.6%,病死率为35.7%。结论胆管乳头状瘤临床表现缺乏特异性,该病的确诊最终依赖于病理检查,手术切除病变组织是其主要治疗方法。Objective To explore the clinical manifestations,features,diagnosis and treatments of biliary papillomatosis.Methods The clinical data of 7 patients with biliary papillomatosis from 1994 to 2011 were retrospectively analyzed,11 pieces of literature of biliary papillomatosis involving 29 patients were searched and analyzed in the CNKI database.Results Clinical manifestations of biliary papillomatosis were abdominal pain（91.7%） and abdominal pain combined with jaundice（72.2%）.Laboratory examination found TBIL stepping-up（69.4%） and CA19-9 stepping-up（37.5%）.Iconography showed choledochectasia（88.9%）.Canceration rate was 30.6% by histological examination.The recurrence rate was 53.6% and fatality rate 35.7% in the following-up of 28 patients.Conclusion Biliary papillomatosis has no specific clinical manifestations.It may be definitely diagnosed with pathological examination.The main therapeutic method is surgical ablation of lesion tissues.

关 键 词：胆管肿瘤 乳头状瘤 诊断 病理学 临床 

分 类 号：R735.8[医药卫生—肿瘤]