Facile Synthesis of Thioamides via P2Ss-Mediated Beckmann Rearrangement of Oximes  

作　　者：李江胜 程超 张馨睿 李志伟 蔡菲菲 薛媛 刘卫东 

机构地区：[1]Hunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation,School of Chemistry and Biological Engineering,Changsha University of Science&Technology,Changsha,Hunan 410114,China

出　　处：《Chinese Journal of Chemistry》2012年第8期1687-1689,共3页中国化学（英文版）

摘　　要：A facile and efficient approach to the synthesis of secondary thioamides from ketoximes via Beckmann rearrangement has been established, using phosphorus pentasulfide as a dehydrating and thiating agent. It is also efficient for the preparation of primary thiobenzamide from benzaldoxime. This approach features simple-operation, easy-control and good to excellent yields.A facile and efficient approach to the synthesis of secondary thioamides from ketoximes via Beckmann rearrangement has been established, using phosphorus pentasulfide as a dehydrating and thiating agent. It is also efficient for the preparation of primary thiobenzamide from benzaldoxime. This approach features simple-operation, easy-control and good to excellent yields.

关 键 词：THIOAMIDES OXIMES phorphorus pentasulfide Beckmann rearrangement iminocarbocation 

分 类 号：TQ460.31[化学工程—制药化工] TS202.3[轻工技术与工程—食品科学]