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机构地区:[1]大连医科大学附属第一医院肿瘤科,辽宁大连116011
出 处:《中国公共卫生》2012年第9期1156-1158,共3页Chinese Journal of Public Health
基 金:辽宁省教育厅2010年度高等学校科研计划项目(L2010121)
摘 要:目的调查和分析辽宁省大连地区存活≥5年非小细胞肺癌患者的生活质量现状。方法 2007年1月—2011年8月在大连医科大学附属第一医院肿瘤科就诊的39例存活≥5年非小细胞肺癌患者,对其进行肿瘤患者生活质量核心问卷QLQ-C30(EORTC-QOL30)评估,并与42例确诊后1年内仍存活的同龄、同性别非小细胞肺癌患者(对照组)的测试结果进行比较。结果长期存活组患者EORTC-QLQ-C30生活质量问卷功能部分各指标得分[躯体功能(68.12±12.90)分、角色功能(63.44±11.05)分、认知功能(72.51±13.26)分、情绪功能(70.38±13.69)分、社会功能(62.46±10.73)分]均高于对照组患者的(56.47±10.85)、(52.83±10.96)、(58.64±11.39)、(57.42±12.17)、(53.91±9.25)分(P<0.05);长期存活组患者EORTC-QLQ-C30生活质量问卷整体质量分和经济困难条目得分分别为(68.35±14.70)和(50.22±11.46)分,分别高于和低于对照组患者的(42.61±10.59)和(74.05±15.93)分(均P<0.01)。结论大连地区存活≥5年非小细胞肺癌患者生活质量现状较好。Objective To survey and analyze the quality of life among patients with non-small cell lung cancer (NSCLC) surviving more than 5 years in Dalian city. Methods A total of 39 NSCLC patients surviving more than 5 years were selected from Dalian to take a survey with European Organization for Research and Treatment of Cancer Core Qadlity of Life questionnaire (EORTC-QOL-30) from January 2007 to August 2011. Another 42 NSCLC patients matched with same age and sex and surviving 1 year were selected as control group. Results Functional scores of EORTC-QOL-30 ,including physical function ( 68. 12 ± 12. 90 ), role function ( 63.44 ± 11.05 ), cognitive function (72. 51 ± 13.26 ), emotional function (70. 38 ± 13.69 ), and social function (62.46 ± 10. 73 ) in 5-year surviving group were significantly higher than those in the control group (56. 47 ± 10. 85,52. 83 ± 10.96,58.64 ± 11.39,57.42 ± 12. 17, and 53.91±9. 25, respectively). However, symptomatic scores of the 5-year surviving group were significantly lower than those in the control group ( t = 2. 089 - 3. 671, P 〈 0. 05 - 0. 01 ). Total quality score of EORTC-QOL-30 was 68.35 ± 14. 70 in the 5-year surviving group, which was significantly higher than that in the control group ( 42.61 ± 10. 59, t =3. 275 ;P 〈 0. 01 ), but the score of financial straits item was 50. 22 ± 11.46 in the 5-year surviving group, which was significantly lower than that in the control group (74. 05 ± 15.93, t = 2. 790 ; P 〈 0. 01 ). Conclusion Quality of life is well among NSCLC patients surviving more than 5 years in Dalian city.
关 键 词:肺癌 非小细胞 存活≥5年 生活质量 EORTC—QOL-30问卷
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