408例非霍奇金淋巴瘤侵犯骨髓与并发白血病的临床观察  

CLINICAL OBSERVATION OF 408 NON-HODGKIN′S LYMPHOMA BONE MORROW INVATION OR COMPLICATION WITH LYMPHOMA CELL LEUKEMIA

作　　者：董群生[1] 闵碧荷[1] 王健民[1] 

机构地区：[1]第二军医大学附属长海医院,上海200433

出　　处：《白血病》2000年第2期70-72,共3页

摘　　要：目的 :观察非霍奇金淋巴瘤 (NHL )骨髓侵犯 (BMI)或并发淋巴瘤细胞性白血病 (L MCL )后 9种变量与预后的关系。方法 :对 40 8例 NHL 的 9种变量与预后的关系进行了对比分析。结果 :NHL 出现骨髓受累后与未受累组 1a、3a和 5 a的生存率有显著性差异 (P<0 .0 5 )。BMI或 L MCL 患者的预后与多种因素相关。其中早期诊断和合理化疗是长期存活的主要可操作因素之一。结论 :NHL 出现 BMI或 L MCL 后预后较差 ,特别是 L MCL治疗更为困难 ,但仍有完全缓解和长期存活的机会。Objective:To investigate the prognosis of bone morrow invasion (BMI) or complication with lymphoma cell leukemia(LMCL) in Non Hodgkin′s lymphoma(NHL). Methods:To analysis the correlation of 9 factors and prognosis.Results: The prognosis of BMI and LMCL patients were significantly bader than those in controls ( P <0.05).We find that prognosis of spread to BM in NHL is associated with many factors,in which early diagnosis and stronger chemotherapy are two of most principal factors in long period survival.Conclusion:Although it is difficult to treatment of BMI or LMCL,but the change of long period survival is exist still.

关 键 词：非霍奇金淋巴瘤 白血病 骨髓侵犯 

分 类 号：R733[医药卫生—肿瘤]