青光眼手术患者生活质量的评价  

Quality of Life in Patients with Glaucoma Following Antiglaucoma Surgical Management

作　　者：张亚辉[1] 王若洁[1] 张加裕[2,3] 蔡剑秋[1] 

机构地区：[1]温州医学院附属第二医院眼科,325027 [2]温州医学院附属第三医院眼科 [3]瑞安人民医院眼科,瑞安325200

出　　处：《医学研究杂志》2012年第8期64-67,共4页Journal of Medical Research

基　　金：浙江省老龄科研中心项目(ZRCA201018)

摘　　要：目的评价青光眼手术患者的生活质量(QOL)。方法横断面研究。应用中文版国家眼科研究所-视功能调查问卷-25对54例复合式小梁切除术后4～6个月(下文简称为"术后")青光眼患者生活质量进行量表调查,选择50例正常人作为对照。结果青光眼患者术后QOL总分(59.12±20.12)比对照组总分(87.55±5.96)明显偏低,差异有统计学意义(t=5.381,P=0.000);除色觉外,其他领域得分均低于对照组,差异均有统计学意义(P均<0.05);在"眼部疼痛"、"社会功能"、"色觉"领域得分较高,均>70分。分组分析显示:不同性别(t=0.750,P=0.456)、不同青光眼类型(t=0.750,P=0.457)、不同青光眼持续时间(t=1.594,P=0.117)QOL得分差异无统计意义;术后停止药物治疗组QOL得分(67.49±19.30)高于术后继续药物治疗组(52.89±16.45),差异具有统计学意义(t=3.001,P=0.004);按就诊时病情严重程度分3级分析显示不同组间QOL得分差异有统计学意义(F=17.64,P=0.000);文化程度和经济收入对青光眼患者术后QOL得分差异无统计学意义(前者F=1.427,P=0.250;后者F=1.605,P=0.211)。结论青光眼手术患者生活质量较正常人明显偏低,其中就诊时病情程度轻、术后无需药物治疗的患者生活质量相对较高。Objective To evaluate and analyze the quality of life （QOL）in patients with glaucoma following antiglaueoma surgical management. Methods It was a cross - sectional study. The QOL was evaluated with a Chinese version of the 25 - item National Eye In- stitute Visual Function Questionnaire （NEI -VFQ25 ） on 54 glaucoma patients with combined trabeculectomy after 4 -6 months（ hereinaf- ter referred to as ＂postoperation＂ ）. 50 normal participants with the same condition except glaucoma were Selected as control group. The data were analyzed Using SPSS16.0. Results The global scores of QOL in participants after combined trabeculeetomy（59. 12 ~ 20.12） were significantly lower than the control group（ 87.55 ~ 5.96） , and there was a significant difference between the two groups（ t = 5. 381 , P = 0. 000）. The scores of all the items in the glaucoma were all lower than those in the control group except for ＂ color vision＂. And therewas significant difference in all the items between the two groups （ P 〈 0.05 ）. The scores of ＂ocular pain＂, ＂social function＂ and ＂ocular vision＂ items were high, which were all higher than 70. There was no significant difference in different gender （ t = 0. 750,P = 0. 456） , different types of glaucoma （ t = 0. 750 ,P = 0. 457 ） and different duration time of glaucoma（ t = 1. 594 ,P = 0.117 ）. The scores of the pa- tients（67.49 ± 19.30） who stopped using medication after surgery were higher than those of the patients（52.89 ± 16.45 ） who still used medication after surgery. There was a significant difference between the two groups （t = 3. 001, P = 0. 004）. The scores of different de- gree severity of glaucoma were different. There was significant difference among the three degree severity groups （F = 17.64, P = 0. 000）. The different culture levels and incomes in patients did not affect the scores of QOL （ The former F = 1. 427, P = 0. 250 ; the latter F = 1. 605, P = 0.211 ）. Conclusion The QOL in patients after

关 键 词：青光眼 生活质量 国家眼科研究所-视功能调查问卷-25 

分 类 号：R775[医药卫生—眼科]