乌鲁木齐地区汉族、维吾尔族胃食管反流病患病状况调查  

An investigation for gastroesophageal reflux disease of Han Chinese and Uygur in Urumqi

作　　者：木尼拉.艾尼瓦尔 牛春燕 米娜娃尔.霍佳 

机构地区：[1]新疆医科大学第一附属医院干部内三科,乌鲁木齐830054 [2]西安医学附属医院消化内科,西安710077

出　　处：《新疆医科大学学报》2012年第9期1257-1261,共5页Journal of Xinjiang Medical University

基　　金：陕西省教育厅科研基金(09JK710)

摘　　要：目的了解乌鲁木齐地区汉族、维吾尔族胃食管反流病(GERD)的发病特点及可能相关的危险因素。方法对在门诊行健康体检的汉族、维吾尔族各500名,应用标准方法和GerdQ量表诊断、分析胃食管反流病在2个民族的发生率、相关危险因素,并比较差异。结果 (1)应用GerdQ量表诊断维吾尔族GERD 175例(发生率35%),汉族GERD130例(发生率26%),维吾尔族GerdQ评分(7.35±2.7)分,高于汉族的(6.55±2.1)分(P<0.005)。维吾尔族男性GerdQ评分(7.55±2.8)分,高于女性的(6.85±2.5)分(P<0.05);按照标准方法诊断汉族维吾尔族GERD 155例,发生率31%,GERD 121例,发生率24.2%。2种诊断方法的诊断率差异无统计学意义。(2)维吾尔族GERD发生率显著高于汉族(P<0.01);维吾尔族男性的发生率高于维吾尔族女性(P<0.005)及汉族男性(P<0.01),差异均有统计学意义。(3)2个民族女性GERD发生均与职业相关(P均<0.01),维吾尔族男性GERD与职业、饮酒相关,汉族男性GERD与职业、饮酒、肉食有关。结论 GerdQ量表诊断GERD与标准方法具有良好的一致性,可用于GERD的临床诊断;维吾尔族GERD发生率高于汉族;性别、职业、饮酒、饮食习惯是乌鲁木齐地区GERD发病的主要危险因素。Objective To investigate Urumqi, Han, Uygur gastroesophageal reflux disease （GERD） disease characteristics, and potential relative risk factors. Methods Five hundred Han and five hundred Uygur residents respectively for health examination were included, each of them accomplished a GERD question- naire （GerdQ）, then accepted endoscopy inspection and proton pump inhibitor test. Results （1） There were 130 Han Chinese （incidence 26%） and 175 Uygur （incidence 35%） GERD were detected according to GerdQ standard; there were 121 Han Chinese （incidence was 24.2%） and 155 Uygur （incidence was 31%） GERD were detected according to classic diagnostic criteria. （2） Uygur GERD incidence was higher than that of Han nationality （P 〈0.01）, Uygur male GERD incidence was higher than that of Uygur female （P 〈0. 005） and Han nationalyty male （P〈0.01）. （3） Female GERD of two populations were all related to occupation; Uygur male GERD was related to occupation and drinking; Han nationalyty male GERD was related to occupation, drinking and meat. Conclusion GerdQ possesses a good compatibility with classic diag nostic criteria and can be used to clinical diagnosis for GERD; Uygur GERD incidence is higher than that of Han nationalyty; gender, occupation, drinking and meat are the main risk factors of GERD in Urumqi.

关 键 词：汉族 维吾尔族 胃食管反流病(GERD) 发生率 危险因素 

分 类 号：R57[医药卫生—消化系统]