急性缺血性脑血管病患者血清内皮素以及血糖、肌酐、尿素氮水平的研究  

Study on levels of serum endothelin,blood glucose,creatinine and blood urea nitrogen in patients with acute ischemic cerebrovascular disease

作　　者：赵华头[1] 汪杏[1] 徐旭然[1] 严婷婷[1] 

机构地区：[1]江苏省南京市高淳县人民医院急诊科,江苏南京211300

出　　处：《实用临床医药杂志》2012年第13期90-92,共3页Journal of Clinical Medicine in Practice

摘　　要：目的研究急性缺血性脑血管病患者血清内皮素以及血糖、肌酐、尿素氮水平变化规律,探讨神经功能缺损程度与血清内皮素水平之间的关系。方法对照分析急性缺血性脑血管病患者与同期非神经系统疾病患者的血清内皮素以及血糖、肌酐、尿素氮水平。结果急性脑梗死组患者血糖以及ET-1水平明显高于对照组,其他指标差异无统计学意义。血清ET-1水平与神经功能缺损程度具有显著的正相关性。结论防治胰岛素抵抗可以作为防治急性缺血性脑血管病的有效措施。血清ET-1水平可以作为急性缺血性脑血管病的敏感监测指标,对于预测患者预后具有重要意义。Objective To study levels of the acute ischemic cerebrovascular disease in patients with serum endothelin and blood glucose,creatinine,blood urea nitrogen,and explore the relationship between the degree of neurological deficit and serum endothelin levels.Methods The serum endothelin and levels of blood sugar,creatinine,and blood urea nitrogen between patients with acute ischemic cerebrovascular disease and patients with non-nervous system disease were comparatively analyzed.Results The blood glucose and ET-1 levels of patients with acute cerebral infarction were significantly higher than those of patients in the control group.The differences of the other indicators were not statistically significant.There was significant positive correlation between serum ET-1 levels and the degree of neurological deficits.Conclusion The prevention and treatment of insulin resistance can be used as an effective measure to prevent and treat acute ischemic cerebrovascular disease.Serum ET-1 levels can be used as sensitive indicators for monitoring of acute ischemic cerebrovascular disease,and of great significance for predicting the prognosis of patients.

关 键 词：急性缺血性脑血管 血清内皮素 神经功能缺损 血糖 肌酐 尿素氮 

分 类 号：R743[医药卫生—神经病学与精神病学]