盐酸环喷托酯与复方托比卡胺在白内障超声乳化术中的散瞳效果比较  

A comparative analysis of mydriasis between cyclopentolate hydrochloride and compound tropicamide in phacoemulsification

作　　者：华欣[1] 王冬艳 庄朝荣[1] 于有江 马晓蓉[1] 

机构地区：[1]江苏省苏北人民医院 [2]扬州环资学院医学系,江苏扬州225001

出　　处：《实用临床医药杂志》2012年第15期86-87,90,共3页Journal of Clinical Medicine in Practice

摘　　要：目的比较盐酸环喷托酯与复方托比卡胺在老年性白内障超声乳化联合人工晶状体植入术中的散瞳效果。方法老年白内障患者120例,随机分为2组,每组各60例。试验组为盐酸环喷托酯组,对照组为复方托比卡胺组。于术前点药3次,每次间隔5 min,观察并记录术前、注入黏弹剂后、超声乳化完成后瞳孔直径,比较起效时间和有效超声乳化时间,并进行统计学分析。结果 2药于点药结束后20 min左右均能达到最大瞳孔直径,2组药物起效时间和最大瞳孔直径无统计学差异;盐酸环喷托酯组与复方托比卡胺组最大孔径维持时间分别为瞳孔开始回缩时间分别为(102±13)min与(89±12)min,睫状肌调节恢复时间两组分别为(13.2±2.6)h和(9.6±2.5)h,两者有统计学差异。结论盐酸环喷托酯组与复方托比卡胺组相比,虽然在睫状肌调节能力的恢复时间相对较慢,但其在术中维持最大孔径时间较长,并且睫状肌调节能在1天内恢复,因此盐酸环喷托酯可作为白内障超声乳化良好的散瞳剂。Objective To compare the effect of mydriasis between cyclopentolate hydrochloride and compound tropicamide in phacoemulsification and intraocular lens implants（IOLs）.Methods A total of 120 patients with geriatric cataract were randomly divided into cyclopentolate hydrochloride（group A） and compound tropicamide（group B）.Before operation,dropping maydriatric was done three times every 5 minutes.The pupil diameter was observed and recorded before operation and after sodium hyalurona was injected and ultrasonic emulsification was finished.The onset time and effective ultrasonic emulsification time were compared and statistically analyzed.Results About 20 minutes after instillation the two groups,pupils reached maximum diameter.The recession time in the treatment group and the control group were（102±13） min and（89±12） min,and the adjustment ability recovery time of ciliaris were（13.2±2.6） h and（9.6±2.5） h.The difference between two groups was significant.Conclusion Though the adjustment ability recovery of ciliaris of group A was slower than group B,its maintaining time of pupils in operation was longer,and ciliary muscle adjustment could recover within one day.Cyclopentolate hydrochloridecan provides perfect pupil dilation for cataract ultrasonic emulsification.

关 键 词：盐酸环喷托酯 复方托比卡胺 白内障超声乳化术 散瞳症 

分 类 号：R776.1[医药卫生—眼科]