电场对肿瘤的治疗作用及机制研究进展  

Research progress in the effect and mechanism of electric field in treating tumors

作　　者：佟洁琼[1] 刘睿婷[2] 孔维超[3] 唐劲天[1] 

机构地区：[1]北京中医药大学微生物与生化药学系,100102 [2]北京.清华大学工程物理系医学物理与工程研究所,100084 [3]北京,清华大学粒子技术与辐射成像教育部重点实验室,100084

出　　处：《国际生物医学工程杂志》2012年第4期224-229,共6页International Journal of Biomedical Engineering

基　　金：国家自然科学基金面上项目（81172120）;中国博士后科学基金面上资助项目（20100480308） ;;

摘　　要：电场治疗肿瘤是将电工技术应用于肿瘤治疗的一项多学科交叉综合性的应用研究，具有安全、适用性强、参数容易控制的特点，近年来倍受关注。目前研究或应用的电场类型主要有脉冲电场和直流电场，均通过改变肿瘤生长的内环境，使之产生病理性变化而死亡。中频交变电场是一种新型的肿瘤治疗电场，应用前景广阔。综述了3种电场的抗癌效应及作用机制在国内外的研究进展。Treating tumors with electric field is an interdisciplinary integrated and comprehensive research which applies electro-technology to tumor treatment. This therapy has the characteristics of safe, practical to its users and the parameters are easily to be controlled, which has attracted considerable attention in recent years. The main types of electric field in current research or application are pulsed electric field and direct current electric field. Both of the types can change the environment where tumors grow with different mechanisms, and the tumors would be killed through their pathological changes. Alternating electric field in intermediate frequency is a new type of tumor treating field, which has a promising application prospect. This article reviews the international and domestic research progress of the effects and mechanisms of the three kinds of electric fields used in the treatment of tumors.

关 键 词：电场 抗癌效应 中频交变电场 作用机制 

分 类 号：R730[医药卫生—肿瘤]