MRI及脑电图对亚临床期肝性脑病的诊断价值  

Diagnostic value of MRI and EEG for subclinical hepatic encephalopathy

作　　者：朱明[1] 李杰[1] 郁冰冰[1] 杨晓[1] 李海军[1] 杨震[1] 孙钢[1] 

机构地区：[1]济南军区总医院医学影像科,济南250031

出　　处：《中华消化病与影像杂志（电子版）》2012年第1期36-38,共3页Chinese Journal of Digestion and Medical Imageology(Electronic Edition)

摘　　要：目的探讨核磁共振成像(MRI)、脑电图(EEG)对亚临床期肝性脑病患者的诊断价值。方法对21例(男15例,女6例)多种原因引起的经临床检查证实的SHE患者行脑部MRI平扫及EEG检查,并测定血氨水平。结果 21例患者MRI阳性者17例,17例(81%)表现为双侧苍白球、15例(71%)表现为中脑被盖对称性T1WI,2例在垂体前叶出现短T1信号,相应部位T2WI、T2FLAIR、DWI序列呈等信号;EEG异常者19例(90%),主要表现为基本节律变慢,仍可见α节律,可见散在性θ波。结论亚临床期肝性脑病患者MRI及EEG检查具有特征性表现,表明获得性脑部变性及脑电生理异常,MRI结合EEG对亚临床期肝性脑病具有重要的诊断价值。Objective To analyze the magnetic resonance imaging （MRI） and Electorence phalogram（EEG）findings in patients with subclinical hepatic encephalopathy（SHE）and evaluate the role of MRI and EEG in the diagnosis of SHE. Methods MRI,EEG were performed and plasma ammonia levels were mersured in twenty-one patients（15 male, 6 female） diagnosed as SHE based on clinical examinations. Results 17 patients of all the 21 patients showed positive MRI signals, specifically, bilateral globus pallidus of 17 patients （81%） and midbrain tegmentum of 15 patients （71%） showed symmetry on T1WI. And anterior pituitary of 2 cases showed short T1 signal, with corresponding regions showed equisignal on T＇2WI, T2FLAIR, DWI. 19 patients had abnormal EEG findings characterized by lowered basic rhythm and sporadic 0 wave. Conclusions Abnormal EEG findings or MR signals in the brain are common in patients with SHE.MRI may help identify acquired hepatiocerebral degeneration,and EEG allows detection of abnormal waves.MRI and EEG are reliable techniques in the diagnosis for SHE.

关 键 词：亚临床期肝性脑病 磁共振成像 脑电图 

分 类 号：R747.9[医药卫生—神经病学与精神病学]