IL-6和超敏C反应蛋白在鉴别结核性及恶性胸腔积液中的价值  

Use of IL-6 and high sensitive c-reactive protein in differential diagnosis of tuberculous pleural effusion and malignant pleural effusion

作　　者：兰四友[1,2] 张德芬[1,2] 杨小琼[1,2] 李国平[1,2] 邓述恺[1,2] 王荣丽[1,2] 

机构地区：[1]泸州医学院附属医院呼吸内科,四川泸州646000 [2]泸州医学院附属医院急诊科,四川泸州646000

出　　处：《四川医学》2012年第8期1343-1345,共3页Sichuan Medical Journal

摘　　要：目的探讨IL-6和HS-CRP在鉴别结核性及癌性胸腔积液中的作用。方法收集60例结核性胸腔积液和70例恶性胸腔积液患者的血清和胸腔积液标本,分别检测其的IL-6和HS-CRP的浓度水平,并比较两组胸腔积液IL-6和HS-CRP的浓度差别。结果在结核性胸腔积液患者中胸腔积液、血清的IL-6和HS-CRP的浓度的水平分别较恶性胸腔积液明显增高,胸腔积液患者胸腔积液及血清IL-6和HS-CRP浓度水平呈相关性。结论在胸腔积液、血清的IL-6和HS-CRP浓度水平检测可作为鉴别结核性胸腔积液和恶性胸腔积液的重要指标。Objective To investigate effeet of IL-6 and high sensitive C-reactive protein in differential diagnosis of tuber- eulous pleural effusion and malignant pleural effusion. Methods Samples of serurn and pleural effusion from 60 eases of tubercu- lous pleural effusion and 70 eases of malignant pleural effusion were collected, IL-6 and HS-CRP levels in samples of serum and pleural effusion were obtained, and the diffirenee of IL-6 and HS-CRP level in two groups of pleural effusion was to be compared. Results The IL-6 and HS-CRP levels of tuberculous pleural effusion group were higher than that of malignant pleural effusion group respectively （P 〈 0. 05）, and the IL-6 and HS-CRP levels of two groups showed courelation. Conclusion The detection of IL-6 and HS-CRP levels of serum and malignant pleural effusion is one of the most important test in differential diagnosis of tuber- eulous tleural effusion and malignant pleural effusion.

关 键 词：IL-6 超敏C反应蛋白 胸腔积液 

分 类 号：R730.4[医药卫生—肿瘤]