日食性视网膜病变中的微小黄斑损伤  

Mini macular lesions in eclipse retinopathy

作　　者：马凯[1] 李志华[1] 熊颖[1] 莫斌[1] 姚宁[1] 刘宁朴[1] 

机构地区：[1]首都医科大学附属北京同仁医院 北京同仁眼科中心 北京市眼科学与视觉科学重点实验室,100730

出　　处：《眼科》2012年第4期244-247,共4页Ophthalmology in China

基　　金：国家自然科学基金(30772378)

摘　　要：目的观察日食性视网膜病变微小黄斑损伤的表现及预后。设计回顾性病例系列。研究对象2009年日食发生后就诊于北京同仁医院的黄斑损伤患者6例(11眼)。方法回顾患者的临床表现及相干光断层扫描(OCT)、眼底自发荧光、多焦视网膜电图(mfERG)、微视野等检查结果,对其视力损害恢复情况以及黄斑病变辅助检查结果进行分析。随访2~18个月。主要指标视力、OCT、眼底自发荧光检查结果。结果 6例(11眼)OCT检查均发现黄斑中心凹视网膜感光细胞内节和外节层(IS/OS层)断裂。其中7眼眼底自发荧光可见黄斑细小暗点,彩色眼底像表现为相应的细小黄点。微视野、mfERG和荧光素眼底血管造影检查未见异常。就诊时视力0.6~0.8,1周~1个月时视力均1.0以上。结论 OCT和眼底自发荧光检查能及时发现日食性视网膜病变中的微小黄斑损伤,此病视力恢复较好。Objective To observe the manifestation and prognosis of mini macular lesions in eclipse retinopathy. Design Retro- spective case series. Participants Six patients （11 eyes） with macular lesions from Tongren Hospital after the eclipse happened in 2009 were included into analysis. Methods Optical coherence tomography （OCT）, autofluorescence photography, micro visual field and multi- focal electroretinogram （mfERG） in all 6 patients were examined and followed up. Follow-up time was 2-18 months. Main Outcome Measures Visual acuity, OCT, and autofluorescence changes. Results Rupture of photoreceptor outer segment layer and inner layer of retinal pigment epithelium （RPE） in the fovea of the all 11 affected eyes was found on OCT images. Hypo^fluorescence in the fovea on autofluorescence photographs and yellow spot on color fundus photographs were found. In 7 eyes the results of the other auxiliary exam- inations were normal. Visual acuity at first visit was 0.6-0.8, and 1-4 weeks later visual acuity was 1.0 or better in all patients. Con- clusion Mini macular lesions in eclipse retinopathy can be found promptly with OCT and autofluorescence photography. Visual recovery of this lesion is better. （Ophthalmol CHN, 2012, 21： 244-247）

关 键 词：日食性视网膜病变 黄斑损伤 

分 类 号：R774.1[医药卫生—眼科]