右旋美托咪啶对小儿七氟醚麻醉苏醒期躁动及血流动力学的影响  

The effect of dexmedetom idine to seroflurance emergence agiation and hemody namics

作　　者：刘芳翔[1] 

机构地区：[1]湖南中医药高等专科学校附属第一医院,湖南株洲412000

出　　处：《中外医疗》2012年第24期24-25,共2页China & Foreign Medical Treatment

摘　　要：目的探讨右旋美托咪啶对用七氟醚麻醉手术后苏醒期躁动的治疗效果及其对患儿血流动力学的影响。方法究选择2011年1月—2011年12月在该院用七氟醚实施全麻手术的儿童63例,随机将其分为对照组、A1组、A2组、每组均为21例。3组在手术结束前注射0、0.2、0.4μg/kg右旋美托咪啶。观察和比较各组患儿苏醒期的躁动情况以及血流动力学的变化。结果 A1组和A2组与对照组比较,两组的躁动例数和心律失常与对照组差异有统计学意义(P<0.05)。A1组与A2比较,A2组躁动、咳呛和咽部疼痛例数和发生率均显著低于A1组。结论右旋美托咪啶可以有效缓解小儿七氟醚全麻苏醒期躁动发生,改善血流动力学水平,可以在临床上加以推广。Objective Investigate the treatment effects of dexmedetomidine on restlessness after sevoflurane anesthesia operation and its effect on hemodynamics in children. Methods Selected 63 cases children under general anesthesia with sevoflurane from 2011 January to 2011 december in our hospital.They were randomly divided into control group, A1 group, A2 group, with 21 cases in each group.Before operation,three groups were injected dexmedetomidine 0, 0.2, 0.4 μg/kg. Observated and comparised restlessness and hemodynamic changes of children in each groups. Results Compared with the control group, the number of restlessness patients number and arrhythmia were significant（P〈0.05）. The cases number of choke cough and throat pain in group A2 were significantly lower than A1 group.Conclusion Dexmedetomidine can effectively alleviate the happen of restlessness, improve hemodynamic level, can be used widely in clinical.

关 键 词：右旋美托咪啶 小儿 七氟醚 苏醒期躁动 血流动力学 

分 类 号：R749.3[医药卫生—神经病学与精神病学]