腹腔镜直肠癌根治术保留盆腔植物神经效果分析  被引量:9

Effective analysis after laparoscopic radical resection of rectal cancer with pelvic autonomic nerve preservation

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作  者:乔唐 王道荣 徐永建 陈平 李清国 

机构地区:[1]扬州大学临床医学院胃肠外科,江苏扬州225001

出  处:《中国现代普通外科进展》2012年第8期613-616,共4页Chinese Journal of Current Advances in General Surgery

摘  要:目的:探讨在腹腔镜直肠癌根治手术中保留盆腔植物神经(PANP)对男性局部复发率、生存率和术后生活质量的影响。方法:不同时期的2组腹腔镜直肠癌根治手术病人,其中非保留盆腔植物神经组34例,保留组88例,回顾性分析比较2组患者的局部复发率、5年存活率及术后排尿功能和性功能。结果:两组均顺利完成手术。其中保留植物神经组82例获得随访,未保留组28例获得随访。局部复发率保留植物神经组为7.3%(6/82),未保留组为7.1%(18/28);5年存活率保留植物神经组为84.2%(69/82),未保留组为82.1%(23/28),2组差异无统计学意义(P>0.05)。排尿功能障碍保留植物神经组为28.1%(23/82),未保留组为60.7%(17/28);勃起功能障碍保留植物神经组为24.4%(20/82),未保留组为67.9%(19/28);射精功能障碍保留植物神经组24.4%(20/82),未保留组71.4%,(20/28),两组比差异均有统计学意义(P<0.05)。结论:腹腔镜直肠癌根治术中保留植物神经功能,对局部复发率和5年存活率无明显影响,但可明显提高患者的生存质量。Objective: To explore the relationship to rate of local recurrence, rate of survival and quality of life for colorectal cancer in laparoscopic radical surgew with pelvic autonomic nerve preservation(PANP). Methods: Two groups of men were retrospectively analyzed in different peri- ods of laparoscopic surgew, including the pelvic autonomic nerve preservation group(study group) of 88 cases, and the non-preservation group (control group) of 34 cases on rate of local recurrence, a rate of 5-year survival and urinary function and sexual function. Results, All of the cases were completed successfully. The rate of local recurrence, the PANP group was 7.3% (6/82)and the control group was 7.1%(18/28), (P〉0.05). For the rate of 5-year survival, the PANP group was 84.2% (69/82), and the control group was 82.1%(23/28), (P〉0.05). For the injured urinary function, the group of PANP was 28.1% (23/82), and the control group was 60.7% (17/28), (P〈0.05). For the erectile dysfunction, the group of PANP was24.39% (20/82), and the control group was 67.9% (19/28), (P〈0.05). For the ejaculatory disorder, the group of PANP was 24.4% (20/82), and the control group was 71.4%, (20/28), (P〈0.05). Conclusion: The laparoscopic radical surgery with pelvic autonomic nerve preservation in rectal cancer would not increase the focal recurrence rate ,nor reduce the 5-year survival rate, but may evidently improve the life quality of man patients.

关 键 词:直肠肿瘤 腹腔镜 盆腔植物神经 性功能 排尿功能 

分 类 号:R735.37[医药卫生—肿瘤] R730.56[医药卫生—临床医学]

 

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