伴自杀意念重性抑郁障碍患者重复性成套神经心理状态测验分析  

Analysis of repeatable battery for the assessment of neuropsychological status in major depression patients with suicide ideation

作　　者：任燕[1] 杨红[1] 孙宁[1] 周子璇[1] 张克让[1] 黄悦勤[2] 

机构地区：[1]山西医科大学第一医院精神卫生科,太原030001 [2]北京大学第六医院

出　　处：《中华行为医学与脑科学杂志》2012年第9期810-812,共3页Chinese Journal of Behavioral Medicine and Brain Science

基　　金：中国自杀研究合作培训项目（D43TW007273）;山西省青年科技研究基金项目（2010021036）;山西省科技攻关项目（20110313012-1）

摘　　要：目的用重复性成套神经心理状态测验（RBANS）分析伴自杀意念重性抑郁障碍患者认知功能损害特点，探讨自杀意念影响因素。方法对132例伴自杀意念的重性抑郁障碍患者和162例不伴自杀意念的重性抑郁障碍患者用RBANS进行检测。结果1．有无自杀意念重性抑郁障碍患者两组问一般资料比较差异无统计学意义（P〉0．05），伴自杀意念组汉密顿抑郁量表（HAMD）、汉密顿焦虑量表HAMA总分均大于不伴自杀意念组，差异有统计学意义（尸〈0．01）。2．伴自杀意念重性抑郁障碍患者注意因子分[（98．56±17．80）分]低于不伴自杀意念重性抑郁障碍患者组[（105．06±14．34）分，P=0．001]，伴自杀意念重性抑郁障碍患者延时记忆因子分[（80．39±15．36）分]低于不伴自杀意念重性抑郁障碍患者组[（85．96±12．55）分，P=0．001]。3．Logistic回归分析结果显示注意损害、HAMD总分是重性抑郁障碍患者自杀意念的危险因素。结论伴自杀意念重性抑郁障碍患者存在注意损害。Objective To analyze of the characteristics of cognitive function in major depressive disorder patients with suicidal ideation using repeatable battery for the assessment of neuropsychological status （RBANS）, and to explore the risk factors of suicidal ideation Methods 132 depressive patients with suicidal ideation and 162 depressive patients without suicidal ideation were evaluated by RBANS, Using SPSS13.0 to statistic the results, including t test,chi-square test and multiple logistic analysis. Re.suits 1. There were no significant differences in age,gender, education level, marital status, total disease duration, whether for the first time episodes of depression, whether a positive family history of depression between the two groups （P 〉 0.05 ）. The HAMD and HAMA total score were greater in patients with suicide ideation than that without suicidal ideation（P 〈 0.01 ）. 2. The score of attention was lower in patients with suicide ideation （98.56 ± 17.80） than in patients without suicide ideation （ 105.06 ± 14.34） （P = 0. 001 ）. The score of delay memory was lower in patients with suicide ideation （ 80.39 ±15.36） than in patients without suicide ideation （ 85.96 ±12.55 ） （P = 0. 001 ）. 3. Logistic regression analysis showed that attention deficit and HAMD total score were the risk factor of suicide ideation in major depressive patients. Conclusion Attention deficit may exist in major depressive patients with suicide ideation, and attention deficit maybe one of the risk factor of suicide ideation.

关 键 词：自杀 重性抑郁障碍 认知功能 重复性成套神经心理状态测验 

分 类 号：R749.4[医药卫生—神经病学与精神病学]