一种通过文本挖掘发现实时定量聚合酶链式反应实验内参基因的方法研究  

An Approach to Discovery of Reference Control Gene for qRT-PCR Experiment Based on Texting Mining

作　　者：何琳[1] 何娟[1] 沈耕宇[1] 杨波[1] 黄水清[1] 

机构地区：[1]南京农业大学信息管理系,南京210095

出　　处：《现代图书情报技术》2012年第7期109-114,共6页New Technology of Library and Information Service

基　　金：中央高校基本科研业务费专项基金"面向qRT-PCR实验的内参基因挖掘技术研究"(项目编号:KYZ201159)的研究成果之一

摘　　要：综合运用模式匹配、主题识别、信息抽取等多种信息处理技术,从基于文献的角度设计一种面向qRT-PCR实验的内参基因及实验环境的挖掘系统,为qRT-PCR实验提供有价值的内参基因推介参考,可以缩短内参基因筛选的时间,减少实验验证的成本,具有较高的识别正确率。初步的测试结果得到生物学领域专业人员的认可。This paper presents a method for identifying candidate reference control gene based on text mining from PubMed database. It integrates several approaches such as pattern matching, subject recognition and information extraction to find candidate gene and its experiment environment for biology domain specialists. Experiment results show that the method not only has good performance on mining of candidate reference control gene and its environments, but also saves much time and reduces cost.

关 键 词：实时定量聚合酶链式反应实验 内参基因 实验环境 文本挖掘 信息抽取 

分 类 号：Q75[生物学—分子生物学] TP391.1[自动化与计算机技术—计算机应用技术]