帕金森病患者膀胱过动症状评估  

Assessment of concomitant overactive bladder symptoms in Parkinson disease

作　　者：魏雅荣[1] 任肖玉[1] 沈炜娣[1] 干静[1] 刘振国[1] 

机构地区：[1]上海交通大学医学院附属新华医院神经内科,200092

出　　处：《中国神经免疫学和神经病学杂志》2012年第5期346-348,353,共4页Chinese Journal of Neuroimmunology and Neurology

基　　金：国家自然科学基金资助项目(81071025;81171203;81171204);上海市科技委员会基金资助项目(11nm0503300;11410708900;12XD1403800);上海市教育委员会资助项目(10ZZ72)

摘　　要：目的分析PD患者膀胱过动症状(OABS)的患病率、影响因素以及OABS对PD患者生活质量(health related quality of life,HRQL)的影响。方法运用膀胱过度活动症问卷(overactive bladder question-naire,OAB-q)、统一帕金森病评分量表(UPDRS)对115例PD患者进行评估。结果 PD患者OABS患病率47.0%。PD组OABSS得分明显高于对照组(P=0.000);PD组的生活质量得分均低于对照组。年龄及帕金森病严重程度与PD患者OABS严重程度呈正相关。OAB组HRQL得分较非OAB组低(P=0.003)。结论 OABS是PD患者中常见的非运动症状之一,OABS严重影响PD患者生活质量,年龄增长和PD病情恶化可增加OABS的严重程度。Objective To analyze the prevalence and impact factors of overactive bladder symptoms（OABS） and the OABS influence on health related quality of life（HRQL） in patients with Parkinson disease（PD）.Methods The overactive bladder questionnaire（OAB-q） and unified Parkinson disease rating scale（UPDRS） were used to evaluate 115 patients with idiopathic PD.The results were taken from PD patients and compared with those of 123 control subjects.Results The prevalence of OABS in PD patients was 47.0%.Compared with the control subjects,PD patients had higher overactive bladder symptom severity（OABSS） score（P=0.000） and lower HRQL score.PD patients with OABS were lower in HRQL score than PD patients without OABS（P=0.003）.The age and severity of PD were the impact factors of OABS.Conclusions OABS is a kind of common symptom in PD patients,which influenced the HRQL of PD patients seriously.OABS will be worse when the PD patients are older and PD is aggravated.

关 键 词：帕金森病 膀胱过动症状 生活质量 影响因素 

分 类 号：R742.5[医药卫生—神经病学与精神病学]