翼状胬肉切除联合自体角膜缘干细胞移植与联合羊膜移植的疗效比较  

Comparative analysis of surgical excision combined with limbal stem cell transplantation and amniotic membrane transplantation for the treatment of pterygium

作　　者：陈利荣[1] 姚军平[1] 袁铸[1] 张贻转[1] 周宇[1] 高波[1] 

机构地区：[1]武汉科技大学附属天佑医院眼科,中国湖北省武汉市430064

出　　处：《国际眼科杂志》2012年第10期2006-2008,共3页International Eye Science

摘　　要：目的:探讨翼状胬肉手术切除联合自体角膜缘干细胞移植术与联合羊膜移植术临床疗效对比。方法:选择本院2007-03/2010-03收治的角膜缘翼状胬肉患者90例90眼,均单眼手术,随机分为两组,角膜移植组给予手术切除联合自体角膜缘干细胞移植,羊膜移植组给予手术切除胬肉联合羊膜移植治疗,观察两组治疗效果。结果:两组术后随访2a,角膜移植组术后创面愈合时间短于羊膜移植组,差异有统计学意义(P<0.05),角膜移植组术后治愈42例,复发3例;羊膜移植组术后治愈39例,复发6例,两组术后复发率比较,差异有统计学意义(P<0.05)。结论:手术切除联合角膜缘干细胞移植治疗翼状胬肉,术后复发率低,并发症少,愈合时间短,值得应用。AIM： To evaluate the clinical efficacy of surgical excision combined with limbal stem cell transplantation, amniotic membrane transplantation for the treatment of pterygium.METHODS：Ninety pterygium patients from March 2007 to March 2010 were randomly divided into corneal transplantation group and amniotic membrane transplantation group, with 45 cases in each group. Corneal transplantation group were treated with surgical excision plus limbal stem cell transplantation, amniotic membrane transplantation group were treated with surgical excision plus amniotic membrane transplantation, the treatment effects of two groups were observed.RESULTS： All the patients in two groups had been followed up for about 2 years; wound healing time of corneal transplantation group was shorter than that of amniotic membrane transplantation group, with the statistically significant difference（P〈0.05）; 42 cases in corneal transplantation group were cured, and recurrence in 3 cases; 39 cases in amniotic membrane transplantation group were cured, and recurrence in 6 cases; and the difference of recurrence rate of two groups was statistically significant（P〈0.05）.CONCLUSION： Surgical excision combined withlimbal stem cell transplantation can treat pterygium, with low recurrence rate, fewer complications, and short healing time.

关 键 词：翼状胬肉 角膜缘干细胞 羊膜 

分 类 号：R779.6[医药卫生—眼科]