Nucleosomes Suppress Spontaneous Mutations Base-Specifically in Eukaryotes  

出　　处：《Science Foundation in China》2012年第1期23-23,共1页中国科学基金（英文版）

摘　　要：A research team led by Professor He Xionglei at the College of Life Sciences,Sun Yat-sen(Zhongshan) University made a breakthrough in understanding how chromatin structure regulates spontaneous mutations,with a discovery that nucleosomes,the structural units of chromatin,suppress mutations from cytosine(C) to thymine(T) in eukaryotic cells.This research appears as a Report in the March 9^(th) issue of Science. Mutations not only provide new materials for evolution,but also are the primary cause of diseases.A research team led by Professor He Xionglei at the College of Life Sciences, Sun Yat-sen （Zhongshan） University made a breakthrough in understanding how chromatin structure regulates spontaneous mutations, with a discovery that nucleosomes, the structural units of chromatin, suppress mutations from cytosine （C） to thymine （T） in eukaryotic cells. This research appears as a Report in the March 9th issue of Science.

关 键 词：真核细胞 核小体 突变 基础 生命科学学院 中山大学 结构调整 结构单元 

分 类 号：Q75[生物学—分子生物学]