100例左右两侧基底神经节梗死致卒中后抑郁的临床观察  

Clinical Observation of Depression after Stroke Induced by Infarction of the Left and Right Basal Ganglia Area

作　　者：王素平[1] 温秀莲[1] 

机构地区：[1]包钢医院神经内科,内蒙古包头014010

出　　处：《包头医学院学报》2012年第4期41-43,共3页Journal of Baotou Medical College

摘　　要：目的:观察左右两侧基底神经节区梗死致卒中后抑郁的发生情况,并比较左右两基底神经节区梗死所致卒中后抑郁之间的差异。方法:选择经CT或MRI证实左侧或右侧基底神经节区单一病灶(除外腔隙性梗死)的患者各50例,左侧50例为A组,右侧50例为B组,用汉密尔顿抑郁量表(HAMD)对入选患者进行评定,对比左、右两侧基底神经节梗死致卒中后抑郁差异情况。结果:左侧基底神经节区梗死的50例患者中,39例均有卒中后抑郁(78%);右侧基底神经节区梗死的50例患者中,14例有卒中后抑郁(28%),左侧高于右侧,差异有统计学意义(P<0.05);左右侧汉密尔顿抑郁量表总分相比,差异有统计学意义(t=4.833,P<0.05),左侧基底神经节区梗死致卒中后抑郁程度重于右侧基底神经节区梗死致卒中后抑郁。结论:左右两侧基底神经节区梗死致卒中后抑郁的发生情况有差异,临床神经心理学工作者应该关注。Objective： To observe the occurrence of depression after stroke induced by infarction of the left and right basal ganglia area and to compare the difference between various kinds of depression after stroke caused by infarction of the left and right basal ganglia area. Methods： 100 cases of single lesion （except lacunar infarction） in either the right or left basal ganglia area con- firmed by CT or MRI were divided into two groups, group A（ 50 cases on the left） and group B （50 cases on the right） , and all of them were evaluated with Hamilton depression rating scale （HAMD） to compare the differences in the depression after stroke be- tweenthe two groups. Results： Of 50 cases of left basal ganglia area infarction, there were 39 cases of depression after stroke （78 % ）. Of 50 cases of right basal ganglia area infarction, there were 14 cases of depression after stroke （28 % ）. The incidence of depression in the cases of left basal ganglia area infarction is higher than that in those of the right basal ganglia area infarction, with significant difference （ P 〈 0.05 ）. There was significant difference in total scores by Hamilton depression scale between group Aand group B（ t = 4. 833 ,P 〈0.05）. The depression after stroke is much more severe in group A than that in Group B. Conclu- sion： There exists difference in the incidence of depression after stroke between the patients with left basal ganglia area infarction and those with right basal ganglia area infarction, which needs to receive much attemtion from Neuropsychologists in clinic.

关 键 词：基底神经节 卒中后抑郁 神经心理学 

分 类 号：R749.1[医药卫生—神经病学与精神病学]