消化道晚期恶性肿瘤患者的预后因素分析  

Survival Analysis of Patients with Advanced Malignant Tumors of the Alimentary Canal

作　　者：王成刚[1] 陈越[2] 蒋霆辉[2] 王涛[2] 张庆荃[2] 吴士延[2] 张微微[2] 沈旭波[2] 方美花[2] 

机构地区：[1]复旦大学附属中山医院分部介入科,上海200052 [2]上海中医药大学附属岳阳中西医结合医院肿瘤科,上海200437

出　　处：《中国临床医学》2012年第4期369-370,共2页Chinese Journal of Clinical Medicine

基　　金：复旦大学附属中山医院复旦青年基金(编号:F0901)

摘　　要：目的:探讨晚期消化道恶性肿瘤患者临床相关因素、介入治疗及中药治疗与预后的关系。方法:回顾分析2006年1月—2011年4月在上海中医药大学附属岳阳医院肿瘤科及复旦大学附属中山医院分部介入科进行治疗的206例晚期消化道恶性肿瘤患者的各种临床因素与生存率的关系,采用Kaplan-Meier生存率分析和Cox比例风险模型进行单因素和多因素分析。结果:是否服用中药、肿瘤分期、肿瘤病理学分化程度及患者的卡氏评分(Karnofsky Performance Status,KPS评分)均与患者1年生存率呈显著相关(P<0.05),而性别、年龄与患者1年生存率无显著相关(P>0.05)。结论:介入治疗在晚期消化道恶性肿瘤的治疗中有稳定病情发展和提高患者生存率的作用,而中药治疗在肿瘤的介入治疗中显示出较好的增效作用。Objective：To explore the factors related with the prognosis of patients with advanced malignant tumors of the ali- mentary canal. Methods： A total of 206 patients with advanced gastrointestinal cancer were followed up and analyzed retrospec- tively from January 2006 to April 2011. The prognosis was analyzed by Kaplan-Meier survival analysis and Cox proportional hazards model. Results： Taking Chinese medicine, tumor stage, tumor pathology and KPS scores of patients were associated with 1 year survival rate （P〈0.05）, while gender and age were not associated with it（P〉0.05）. Conclusion： Intervention treatment can suppress the progression of advanced alimentary canal tumors and improve patient survival rate. Besides, Chinese medicine shows a good synergistic effect in interventional treatment of tumors.

关 键 词：介入疗法 消化道肿瘤 生存分析 

分 类 号：R735[医药卫生—肿瘤]