抗癫痫药物对癫痫患儿认知功能的影响  

Cognitive effects of antiepileptic drugs in children with epilepsy

作　　者：李天苏(综述)[1] 唐久来(审校)[1] 德吴德(审校)[1] 

机构地区：[1]安徽医科大学第一附属医院小儿神经康复科,合肥230022

出　　处：《国际儿科学杂志》2012年第5期510-513,共4页International Journal of Pediatrics

摘　　要：抗癫疴药物在临床上的大量应用及其所造成的认知功能损害和其损害程度是癫痫治疗中值得关注的问题之一。新型抗癫疴药物的出现、多药联合治疗和血药浓度高，增加了抗癫疴药物对认知功能的损害。该文综述传统抗癫疴药物与新型抗癫疴药物对儿童认知的影响，为临床治疗癫痫，提高癫疴患儿的生活质量提供理论依据。The damage to cognitive function caused by the application of antiepileptic drugs in clinic and the extent of damage have become the issues of epilepsy therapy. The new antiepileptic drugs, multi-drug combi- nation therapy and plasma concentration have increased the risk of cognitive function damage. This paper reviews the impacts of traditional anti-epileptic drugs and new antiepileptic drugs on children＇s cognitive functions, in order to provide a theoretical basis to improve the life quality of children with epilepsy.

关 键 词：抗癫疴药物 联合用药 认知功能 

分 类 号：R749.16[医药卫生—神经病学与精神病学]