桑色素/石墨烯修饰电极的制备及对多巴胺的选择性灵敏测定  

Fabrication of Morin Incorporated Graphene Modified Electrode and Its Selective and Sensitive Determination of Dopamine

作　　者：鹿才余[1,2] 王宗花[1,2] 张菲菲[1,2] 夏建飞[1,2] 郭新美[1,2] 夏延致[1,2] 李延辉[1] 

机构地区：[1]青岛大学化学化工与环境学院,山东青岛266071 [2]青岛大学纤维新材料与现代纺织实验室国家重点实验室培育基地,山东青岛266071

出　　处：《分析测试学报》2012年第9期1120-1125,共6页Journal of Instrumental Analysis

基　　金：国家自然科学基金(20975056;81102411);山东省自然科学基金(ZR2011BZ004;ZR2011BQ005);NSFC-JSPS中日合作与交流项目(21111140014);生命分析化学国家重点实验室开放基金(SKLACLS1110);山东省泰山学者资助项目(TS20070711);973计划资助项目(2012CB722705)

摘　　要：在石墨烯纳米片修饰电极(GN/GCE)上,通过电聚合的方法制备了新颖的桑色素/石墨烯复合修饰电极(M/GN/GCE)。以多巴胺(DA)和抗坏血酸(AA)为模型化合物,运用循环伏安法(CV)和差示脉冲伏安法(DPV)考察了该复合修饰电极的电催化行为。在pH 7.0的PBS中,DA和AA分别在0.172 V和-0.183 V产生氧化峰,峰位差达355 mV。与单一修饰电极(桑色素修饰电极(M/GCE)、石墨烯修饰电极(GN/GCE)及裸玻碳电极(GCE))相比,DA在M/GN/GCE上的峰电流显著增大。在优化的实验条件下,DA在2.0×10-8～5.5×10-4mol/L浓度范围内与其峰电流具有良好的线性关系,检出限达9.0×10-9mol/L。A morin/graphene modified glassy carbon electrode（M/GN/GCE） was fabricated by electro-polymerizing morin（M） on the surface of graphene nanosheets（GN）.Taking the dopamine（DA） and ascorbic acid（AA） as model compounds,the electrochemical behaviors of the modified electrode were investigated by using cyclic voltammetry（CV） and differential pulse voltammetry（DPV）.In pH 7.0 phosphate buffer solution（PBS）,the anodic peak potentials of DA and AA were 0.172 V and-0.183 V,respectively,with a peak to peak separation up to 355 mV.In comparison with bare glassy carbon electrode（GCE）,morin modified glassy carbon electrode（M/GCE） and graphene modified glassy carbon electrode（GN/GCE）,the M/GN/GCE has superior electrocatalytic activity toward the oxidation of DA.The results demonstrated that the aromatic structure of M endows it strongly adsorption on GN via π-π stacking which could improve the selectivity and sensitivity for the determination of DA in the presence of AA.The peak currents obtained from DPV were linearly related to the concentrations of DA in the range of 2.0×10^-8-5.5×10^-4 mol/L with a detection limit of 9.0×10^-9 mol/L.

关 键 词：桑色素 石墨烯 修饰电极 多巴胺 选择性测定 

分 类 号：O657.1[理学—分析化学] O623.731[理学—化学]