肾肿瘤相关Wunderlich综合征八例并文献复习  

Wunderlich＇s syndrome associated with renal tumor： a report of 8 eases and literature review

作　　者：陈晓松[1] 欧彤文[1] 张建 李建新 崔昕[1] 何新洲[1] 高伟[1] 王升晗[1] 李进[1] 许建军[1] 

机构地区：[1]首都医科大学宣武医院泌尿外科,北京100053 [2]血管外科

出　　处：《中国医药》2012年第10期1286-1288,共3页China Medicine

摘　　要：目的探讨肾脏肿瘤相关Wunderlich综合征的病因、诊断及治疗原则。方法回顾性分析8例肾脏肿瘤相关Wunderlich综合征患者，超声检查和CT作为术前诊断依据。结果8例中5例患者接受了根治性肾切除术，2例术前CT明确诊断肾血管平滑肌脂肪瘤者行超选择性栓塞治疗，另1例患者保守治疗。8例患者均获存活，术后随访6个月一5年，无肿瘤复发及转移迹象。无再发腹膜后出血及尿毒症发生。结论肾肿瘤相关Wunderlich综合征患者应行CT检查。若出血为恶性肿瘤所致，筋膜外的肾切除术仍是有效的治疗选择。对确诊为良性肿瘤的患者，可应用选择性肾动脉栓塞等保留肾单位治疗。Objective To investigate the cause, diagnosis and management of Wunderlich＇s syndrome associated with renal tumor. Methods Clinical data of 8 cases of Wunderlieh＇s syndrome associated with renal tumor was reviewed. Ultrasonography and Computed tomography （CT） were used as preoperative diagnostic methods. Results Five patients underwent radical nephrectomy and two cases diagnosed of renal angiomyolipomas by CT were treated by superselective embolization. Conservative treatment was adopted in one case. Disease specific survival of the entire cohort was 100%. All these patients had a follow-up for 6 months to 5 years. Nobody suffered from tumour recurrence and metastasis. No retroperitoneal hemorrhage and urinemia were noted. Conclusions Wunderlich＇s syndrome is associated with renal tumor. CT should be performed in all patients. If the bleeding is caused by a malignant turnout, radical nephrectomy is still the treatment of choice. For those with benign tumours, selective renal artery embolization and other renal sparing treatment can be used.

关 键 词：肾肿瘤 Wunderlich综合征 出血 

分 类 号：R737.11[医药卫生—肿瘤]