急性脑穿支动脉梗死患者血脂及血浆高敏C反应蛋白浓度测定的研究  

The levels of high sensitive C-reaction protein and blood lipid in acute penetrating arterial cerebral infarction

作　　者：汪效松[1] 张旭[1] 雷惠新[1] 周瑞玲[1] 

机构地区：[1]福建医科大学省立临床医学院福建省立医院神经内科,福建福州350001

出　　处：《中华脑血管病杂志（电子版）》2012年第4期13-15,共3页Chinese Journal of Cerebrovascular Diseases(Electronic Edition)

基　　金：福建省卫生厅青年科研基金资助项目;基金编号2004-1-22

摘　　要：目的研究中国缺血性卒中亚型(CISS)分型中急性脑穿支动脉梗死患者血脂、血浆高敏C反应蛋白(hsCRP)浓度,判断动脉粥样硬化机制在急性穿支动脉脑梗死中的作用。方法测定60例急性脑穿支动脉梗死患者血总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)及hsCRP浓度,与50例对照组进行比较分析。结果急性穿支动脉疾病所致脑梗死患者,血浆LDL-C、hsCRP浓度水平升高,与正常对照组比较差异有统计学意义(P<0.01)。结论急性穿支动脉脑梗死可能与动脉粥样硬化的病理生理过程有关。Objective To identify the role of pathophysiologic processes of artherosclerosis in patients with acute penetrating arterial cerebral infarction, a Chinese ischemic stroke subclassification （CISS） , through evaluating the levels of blood lipid and high sensitive C-reaction protein. Methods Detecting and comparing the level of blood total cholesterol （TC）, triglyeride （TG）, low-density lipoprotein cholesterol（LDL-C） and high sensitive C-reaction protein （hsCRP） in 60 cases of acute penetrating arterial cerebral infarction and 50 controls. Results The levels of hsCRP, LDL-C in acute perforating branch arterial cerebral infarction group were significantly higher than that of control group（ all P 〈 O. 01 ）. Conclusion The acute penetrating arterial cerebral infarction may associated with the pathophysiologic processes of artherosclerosis.

关 键 词：中国缺血性卒中亚型 穿支动脉梗死 高敏C反应蛋白 血脂 低密度脂蛋白胆 固醇 

分 类 号：R743.3[医药卫生—神经病学与精神病学]