脑卒中患者血清SIL-2R水平变化在预测继发肺部感染中的诊断价值  

Diagnostic value of changes of the serum level of SIL-2R in patients with stroke in the prediction of secondary pulmonary infection

作　　者：郑红[1] 

机构地区：[1]资阳市第一人民医院,资阳641300

出　　处：《成都医学院学报》2012年第3期410-412,共3页Journal of Chengdu Medical College

基　　金：中国高校医学期刊临床专项资金(NO:11221605)

摘　　要：目的探讨脑卒中患者血清SIL-2R水平变化在预测继发肺部感染中的诊断价值。方法选取本院收治的78例脑卒中患者为研究对象,分为脑梗塞组与脑出血组。采用双抗体夹心酶联免疫吸附法(ELISA)检测患者血清中SIL-2R浓度水平;同时观察研究对象中继发肺部感染的患者的SIL-2R水平变化情况。结果脑梗塞组患者中,继发肺部感染比例为18.60%。其中未感染患者SIL-2R平均水平为(348.68±28.39)μg/mL,感染患者平均水平为(425.48±48.35)μg/mL;脑出血组患者中,继发肺部感染比例为17.14%。未感染患者SIL-2R平均水平为(338.69±43.17)μg/mL,感染患者平均水平为(417.39±38.72)μg/mL。因此脑卒中继发感染患者SIL-2R平均水平明显高于未感染患者,差异有统计学意义(P<0.05)。结论血清SIL-2R水平动态变化为反映脑卒中患者免疫功能状态提供了新的检测指标,在预测脑卒中患者继发肺部感染具有一定的诊断意义。Objective To evaluate the diagnostic value of changes of the serum level of SIL-2R in patients with stroke in the prediction of secondary pulmonary infection. Methods 78 cases of stroke patients havewere divided into groups of cerebral infarction and cerebral hemorrhage. SIL-2R levels wasere detected with double antibody sandwich enzyme-linked immunosorbent assay（ELISA） ;At the same timeMeanwbile, SIL-2R serum level variations werewe observed among patients with secondary pulmonary infection in patients with SIL-2R level. Results In the group of cerebral infection, 18. 60% patients bad The ratio of cerebral infarction in patients with secondary pulmonary infection is 18.60%. The average serum level of SIL-2R among The uninfected patients have the average ofwas（348.68＋28.39）μg/mL of SIL-2R,while that among infection patients with average ofwas（425. 48＋48. 35） μg/mL;The ratio of Among patients with cerebral hemorrhage, the occurrence rate of in patients with secondary pulmonary infection iwasl7. 14%. The average serum level of SIL-2R among uninfected patients was Uninfected patients have average the of（338.69±43.17）vg/mL,while that among of SIL-2R,infection in patients with average ofwas（417.39 ±38.72）/zg/mL. Therefore, secondary infection in patients with cerebral strokethe average SIL-2R serum level was higher in cerebral infection patients complicated with secondary pulmonary infection was higher than that of uninfected patients,the difference was statistically significant（P〈0.05）. Conclusion The dynamic changes of SIL-2R level reflect the status of immune function in patients with stroke and provide a new detection index in the prediction of stroke patients with pulmonary infection.

关 键 词：脑卒中 SIL-2R 继发肺部感染 

分 类 号：R743.3[医药卫生—神经病学与精神病学]