牛初乳冲剂增强免疫力的实验研究  

The Experimental Study on Enhancing Immunity of the Bovine Colostrum Granule

作　　者：徐冰[1] 高慧艳[1] 王海玉[1] 王燕[1] 张桂霞[1] 张聪恪[1] 

机构地区：[1]河南省疾病预防控制中心,河南郑州450016

出　　处：《中国医药指南》2012年第26期18-19,共2页Guide of China Medicine

摘　　要：目的观察牛初乳冲剂对小鼠免疫功能的影响。方法 BALB/c小鼠连续灌胃30d后检测碳廓清能力、迟发型变态反应、抗体生成细胞数、血清溶血素水平、巨噬细胞吞噬鸡红细胞能力、NK细胞活性及ConA诱导的脾淋巴细胞转化能力等免疫指标。结果牛初乳冲剂对小鼠的脏/体比值、碳廓清能力及NK细胞活性无明显影响;对迟发型变态反应、抗体生成细胞数、HC50、巨噬细胞吞噬鸡红细胞能力及ConA诱导的小鼠淋巴细胞转化有显著作用。结论牛初乳冲剂能增强小鼠免疫力。Objective To observe the impact of the bovine colostrum granule on immune function in mice.Methods Given BALB/c mice the bovine colostrum granule intragastrically 30 days,we detected immune indicators,including carbon clearance ability,delayed type hypersensitivity,antibody-producing cell count,serum hemolysin level,macrophage phagocytosis of chicken erythrocytes capacity,NK cell activity and ConAinduced lymphocyte transformationability,etc.Results The bovine colostrum granule had no obvious influence on organ weight / body weight,carbon clearance and NK cell activity in mice.However,it had significant effect on delayed type hypersensitivity,antibody-producing cell count,HC50,macrophage phagocytosis of chicken erythrocytes capacity and ConA-induced lymphocyte transformationability.Conclusion The bovine colostrum granule could enhancing Immunity in mice.

关 键 词：牛初乳 免疫功能 小鼠 

分 类 号：R392[医药卫生—免疫学]