急性脑梗死患者血浆P选择素及D-二聚体水平与预后的关系  

The Relations of Plasma P-selectin/D-dimer Levels and Prognosis in Patients with Acute Cerebral Infarction

作　　者：刘礼泉 

机构地区：[1]衡阳市中心医院老年医学科,湖南衡阳421000

出　　处：《医学综述》2012年第19期3304-3305,共2页Medical Recapitulate

摘　　要：目的探讨急性脑梗死患者血浆P选择素及D-二聚体水平与预后关系的临床意义。方法 96例对急性脑梗死患者分别于发病后1、3 d抽取外周静脉血,测定血浆P选择素及D-二聚体水平,并于发病后1、30 d采用斯堪的纳维亚卒中量表(SSS)进行神经功能缺损评分。统计分析P选择素及D-二聚体平均水平(发病后1、3 d平均值)与SSS评分之间的关系。结果轻、中、重型患者发病后P选择素及D-二聚体平均水平依次增高,P选择素及D-二聚体平均水平与SSS下降值呈直线正相关。结论急性脑梗死患者发病后P选择素及D-二聚体平均水平可以作为判断病情和预后的重要指标。Objective To explore the clinical significance of relations between plasma P-selectin/D-di-mer levels and prognosis in patients with acute cerebral infarction. Methods In 96 patients of acute cerebral infarction, peripheral venous blood were collected at 1,3 days after invasion, and neurological deficit scores were calculated by Scandinavian Stroke Scale（SSS） in 1,30 days after invasion. The relations between P-se- lectin/D-dimer average and the SSS score was statistically analyzed. Results The P-selectin/D-dimer levels of, mild, medium and serious patients were gradually increased. The average P-seleetin/D-dimer levels and SSS decline was a positive linear correlation. Conclusion Plasma P-seleetin/D-dimer levels after invasion can be an imoortant index of iudging condition and orognosis of patients with acute cerebral infarction.

关 键 词：急性脑梗死 P选择素 D-二聚体 预后 

分 类 号：R743.3[医药卫生—神经病学与精神病学]