ROC曲线评价弥散加权成像对直结肠癌肝转移灶的检出价值  

Eevaluation in the Detection of Liver Metastases from Colorectal Cancer with Diffusion-weighted Imaging:ROC Curve Analysis

作　　者：沈健[1] 祝跃明[1] 钱海锋[1] 李凤琪 姚丽娣[1] 李海良[1] 

机构地区：[1]浙江省湖州市中心医院放射科,313000

出　　处：《医学研究杂志》2012年第9期102-105,共4页Journal of Medical Research

基　　金：浙江省湖州市科技局基金资助项目(2010YS10)

摘　　要：目的比较磁共振弥散加权成像(diffusion weighted imaging,DWI)与多层螺旋CT(multi-slice CT,MSCT)动态增强扫描对直结肠癌肝脏转移灶的检出率,评价DWI对肝转移的早期诊断价值。方法 53例直结肠癌术后患者,分别行肝脏磁共振DWI扫描和MSCT动态增强扫描,采用受试者工作特征曲线(receive operating characteristic curve,ROC)分析扫描结果。结果DWI诊断方法的曲线下面积(Az)、灵敏度、特异度和阳性预测值分别为0.964、98.9%、88.5%和96.9%,MSCT诊断方法则分别为0.818、91.5%、51.3%和80.2%,两组结果有统计学差异(P<0.05)。结论对于直结肠癌肝转移灶的早期检出及阳性预测,磁共振弥散加权扫描更具优势。Objective To compare the detect rate of diffusion - weighted magnetic resonance imaging （ diffusion weighted imaging, DWI） and dynamic contrast - enhanced spiral CT scan （ Multi - slice CT, MSCT） in the detection of liver metastases from colorectal cancer,and to evaluate the early diagnosis of DWI for liver metastases. Methods 53 cases of colorectal cancer patients after surgery were treated by liver scan and magnetic resonance DWI dynamic contrast- enhanced MSCT scan, using receiver operating characteristic curve （ROC） to analyze the scan results. Results Results of diagnostic methods DWI area under the curve （Az） , sensitivity, specificity and positive predictive values were 0. 964,98.9% , 88.5% and 96.9% , MSCT diagnosis were 0. 818,91.5% , 51.3% and 80.2% , two sets of results are statistically significant （P 〈 0. 05）. Conclusion For early detection of liver metastases and positive predictive of colorectal cancer,DWI had much more advantages.

关 键 词：弥散加权成像 体层摄影 肿瘤转移 肝 

分 类 号：R743.33[医药卫生—神经病学与精神病学]